(5S)-4-Acetyl-1-(4-Chloro-2,6-Difluorophenyl)-5-Cyclohexyl-1,5-Dihydro-3-Hydroxy-2H-Pyrrol-2-One CAS 512178-04-0

Purity 97%+In StockPharmaceutical Standards
CAS No.512178-04-0
Molecular FormulaC18H18ClF2NO3
Molecular Weight369.79 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(5S)-4-Acetyl-1-(4-Chloro-2,6-Difluorophenyl)-5-Cyclohexyl-1,5-Dihydro-3-Hydroxy-2H-Pyrrol-2-One CAS 512178-04-0 chemical structure

Description

The occurrence of (5S)-4-Acetyl-1-(4-Chloro-2,6-Difluorophenyl)-5-Cyclohexyl-1,5-Dihydro-3-Hydroxy-2H-Pyrrol-2-One is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(5S)-4-Acetyl-1-(4-Chloro-2,6-Difluorophenyl)-5-Cyclohexyl-1,5-Dihydro-3-Hydroxy-2H-Pyrrol-2-One (CAS 512178-04-0) is a high-purity analytical reference standard with the molecular formula C18H18ClF2NO3 and a molecular weight of 369.79 g/mol.

Structurally, (5S)-4-Acetyl-1-(4-Chloro-2,6-Difluorophenyl)-5-Cyclohexyl-1,5-Dihydro-3-Hydroxy-2H-Pyrrol-2-One (C18H18ClF2NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 369.79 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (5S)-4-Acetyl-1-(4-Chloro-2,6-Difluorophenyl)-5-Cyclohexyl-1,5-Dihydro-3-Hydroxy-2H-Pyrrol-2-One meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H18ClF2NO3
Molecular Weight369.79 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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