3-(Pyridin-2-yloxy)benzoic acid CAS 51362-30-2
| CAS No. | 51362-30-2 |
| Molecular Formula | C12H9NO3 |
| Molecular Weight | 215.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(Pyridin-2-yloxy)benzoic acid (CAS 51362-30-2), molecular formula C12H9NO3 and molecular weight 215.20 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(Pyridin-2-yloxy)benzoic acid (C12H9NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 3-(Pyridin-2-yloxy)benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H9NO3 |
| Molecular Weight | 215.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Nitrogen Atoms | 1 |
Related Pyridin Standards
- 2-(pyridin-3-yloxy)benzoic acid (CAS 1094325-06-0)
- 2-(Pyridin-4-yloxy)benzoic acid (CAS 1247139-79-2)
- 2-(Pyridin-2-yloxy)benzoic acid (CAS 857540-41-1)
- 3-(Pyridin-3-yloxy)benzoic acid (CAS 697223-52-2)
- 4-(Pyridin-3-yloxy)benzoic acid (CAS 437383-99-8)
- 3-(pyridin-4-yloxy)benzoic acid 780028-19-5 (CAS 780028-19-5)
- 2-(Pyridin-3-ylamino)isonicotinic acid (CAS 1019388-92-1)
- Methyl 2-(pyridin-2-yl)pyrimidine-5-carboxylate (CAS 1068976-90-8)
Recommended Standards
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Why CATO?
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