3-[(6-chloro-4-phenylquinazolin-2-yl)amino]propan-1-ol CAS 51443-54-0
| CAS No. | 51443-54-0 |
| Molecular Formula | C17H16ClN3O |
| Molecular Weight | 313.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-[(6-chloro-4-phenylquinazolin-2-yl)amino]propan-1-ol (CAS 51443-54-0) is a high-purity analytical reference standard with the molecular formula C17H16ClN3O and a molecular weight of 313.78 g/mol.
3-[(6-chloro-4-phenylquinazolin-2-yl)amino]propan-1-ol (C17H16ClN3O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-[(6-chloro-4-phenylquinazolin-2-yl)amino]propan-1-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H16ClN3O |
| Molecular Weight | 313.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
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- (2E)-1-(3-Chlorophenyl)-3-(2,3-dimethoxyphenyl)prop-2-en-1-one (CAS 1801666-51-2)
- 2-(6-(Cyclopropylamino)-4-methylpyridin-3-yl)ethanol (CAS 1355197-35-1)
- N-24:0 (2S-OH) Phytosphingosine (CAS 154801-34-0)
- 4-(Azetidin-3-yloxy)-2,2-dimethylbutanenitrile (CAS 1488101-88-7)
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- 3-(5-(Methylsulfonyl)-1,2,3-thiadiazol-4-yl)aniline (CAS 1710853-16-9)
- Semaglutide impurity 95 (CAS CATO-C4X-222695)
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