5-Bromo-2-methylisonicotinonitrile CAS 51454-48-9
| CAS No. | 51454-48-9 |
| Molecular Formula | C7H5BrN2 |
| Molecular Weight | 197.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Bromo-2-methylisonicotinonitrile (CAS 51454-48-9), molecular formula C7H5BrN2 and molecular weight 197.03 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Bromo-2-methylisonicotinonitrile (C7H5BrN2) is characterized by a nitrile group, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Bromo-2-methylisonicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5BrN2 |
| Molecular Weight | 197.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
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- 6-Bromo-5-azaindole, 97% (CAS 1000342-71-1)
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- 5-Bromo-6-methylpicolinonitrile (CAS 1173897-86-3)
Recommended Standards
- 5-Bromo-2-ethynylphenol (CAS 2228644-88-8)
- 5-Bromo-2-methylnicotinonitrile (CAS 956276-47-4)
- 5-Bromo-2-cyanomethylpyridine, 97% (CAS 312325-72-7)
- 5-Bromo-4-methylnicotinonitrile (CAS 890092-52-1)
- 3-Chloro-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1289197-40-5)
- N-Isobutyryl-2', 3'-Acetyl-Guanosine (CAS 163586-86-5)
- 3-Bromo-2-(piperidin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 2223029-32-9)
- 2-Amino-5-(4-fluoro-3-methoxyphenyl)pyridine (CAS 1314988-51-6)
- 2-(Pyrrolidin-3-ylthio)benzo[d]thiazole hydrochloride (CAS 1420850-00-5)
- Azithromycin CP Impurity Q (CAS 99290-97-8)
- 4-Fluoro-3-hydroxybenzyl alcohol (CAS 934241-78-8)
- 2,4-Dichloro-5-(difluoromethoxy)phenol (CAS 1803791-33-4)
- Myristoyl Pentapeptide-4 (CAS 1392416-25-9)
- Semaglutide impurity 276 (CAS CATO-C4X-2226276)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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