4-(4-Chloro-3-(trifluoromethyl)phenoxy)benzaldehyde CAS 516481-95-1
| CAS No. | 516481-95-1 |
| Molecular Formula | C14H8ClF3O2 |
| Molecular Weight | 300.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(4-Chloro-3-(trifluoromethyl)phenoxy)benzaldehyde is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(4-Chloro-3-(trifluoromethyl)phenoxy)benzaldehyde (CAS 516481-95-1) is a high-purity analytical reference standard with the molecular formula C14H8ClF3O2 and a molecular weight of 300.66 g/mol.
4-(4-Chloro-3-(trifluoromethyl)phenoxy)benzaldehyde (C14H8ClF3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H8ClF3O2 |
| Molecular Weight | 300.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-N-(2-(trifluoromethyl)phenyl)isonicotinamide (CAS 1040055-59-1)
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- 2-Chloro-4-(2-trifluoromethylphenyl)benzoic acid (CAS 1237080-49-7)
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- 6-Chloro-2-(2-trifluoromethylphenyl)benzoic acid (CAS 1261786-21-3)
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Recommended Standards
- 3'-Chloro-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxylic acid (CAS 442670-42-0)
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- (E)-2-(((3-chloro-5-(trifluoromethyl)pyridin-2-yl)imino)methyl)phenol (CAS 303090-94-0)
- 4-Chlorophenyl 4-(trifluoromethyl)benzoate (CAS 23171-01-9)
- 5-Iodo-2-methoxythiazole (CAS 2137792-51-7)
- Methyl 5-(trifluoromethyl)-1H-indole-2-carboxylate (CAS 1362860-89-6)
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- 2-(4-chlorophenyl)cyclopentan-1-amine hydrochloride (CAS 40297-15-2)
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- (4-Aminothiophen-2-yl)boronic acid hydrochloride (CAS 1360465-67-3)
- a2,3-Sialylglycopeptide (CAS 189035-43-6)
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