Tobramycin Impurity N1 CAS 51736-77-7
| CAS No. | 51736-77-7 |
| Molecular Formula | C19H38N6O10 |
| Molecular Weight | 510.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Tobramycin Impurity N1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Tobramycin Impurity N1 (CAS 51736-77-7, C19H38N6O10) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Tobramycin Impurity N1 (C19H38N6O10) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C19H38N6O10 |
| Molecular Weight | 510.54 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Nitrogen Atoms | 6 |
Related Tobramycin Standards
- Tobramycin Impurity 10 (CAS CATO-C4X-220010)
- Tobramycin Impurity 15 (CAS CATO-C4X-220016)
- Tobramycin Impurity 18 (CAS CATO-C4X-220018)
- Tobramycin Impurity 24 (CAS CATO-C4X-220024)
- Tobramycin Impurity 15 (CAS 207670-58-4)
- Tobramycin Impurity 27 (CAS CATO-C4X-220027)
- Tobramycin Impurity 8 (CAS CATO-C4X-22008)
- Tobramycin (CAS 32986-56-4)
Recommended Standards
- 1-N-Ureido Tobramycin (CAS CATO-C4X-22007)
- Cyclohexyl 2-(3,4,5-trifluorophenyl)ethyl ketone (CAS 898778-77-3)
- Ethyl 5-(2-{[6-tert-butyl-3-cyano-4-(trifluoromethyl)pyridin-2-yl]sulfanyl}acetamido)-4-cyano-3-methylthiophene-2-carboxylate (CAS 625377-43-7)
- Methotrexate Diethyl Ester (CAS 43170-88-3)
- Glycyrrhizic Acid Impurity 30 (CAS CATO-C4X-253730)
- Vonoprazan Impurity 222 HCl (CAS 2231094-87-2 (free base))
- Rimegepant Impurity 60 (CAS CATO-C4X-248760)
- rel-(3aR,7aR)-Octahydrofuro[2,3-c]pyridine hydrochloride (CAS 374794-83-9)
- Poly(maleic anhydride-alt-1-octadecene) (CAS 25266-02-8)
- 2,3-Dihydroisoquinoline-1,4-dione (CAS 31053-30-2)
- 3-((Benzofuran-2-ylmethyl)amino)-5-ethyl-6-methylpyridin-2(1H)-one (CAS 135525-72-3)
- 5-Iodo-4-methyl-2-(methylthio)pyrimidine (CAS 2384282-28-2)
- 2-(4-(Benzyloxy)-3-(hydroxymethyl)phenyl)-N-(tert-butyl)acetamide (CAS 1956335-15-1)
- α Bag Cell Peptide (1-9) (CAS 87549-52-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com