| CAS No. | 51746-86-2 |
| Molecular Formula | C8H13N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
The occurrence of 3-(1H-imidazol-4-yl)piperidine dihydrochloride is closely related to a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(1H-imidazol-4-yl)piperidine dihydrochloride (CAS 51746-86-2) is a high-purity analytical reference standard with the molecular formula C8H13N3HCl and a molecular weight of 187.67 g/mol.
The molecular framework of 3-(1H-imidazol-4-yl)piperidine dihydrochloride (C8H13N3HCl) is characterized by a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(1H-imidazol-4-yl)piperidine dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C8H13N3 2*HCl |
| Molecular Weight | 187.67 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |