3-(1H-imidazol-4-yl)piperidine dihydrochloride CAS 51746-86-2

Purity 97%+In StockPharmaceutical Standards
CAS No.51746-86-2
Molecular FormulaC8H13N3
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(1H-imidazol-4-yl)piperidine dihydrochloride CAS 51746-86-2 chemical structure

Description

The occurrence of 3-(1H-imidazol-4-yl)piperidine dihydrochloride is closely related to a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

3-(1H-imidazol-4-yl)piperidine dihydrochloride (CAS 51746-86-2) is a high-purity analytical reference standard with the molecular formula C8H13N3HCl and a molecular weight of 187.67 g/mol.

The molecular framework of 3-(1H-imidazol-4-yl)piperidine dihydrochloride (C8H13N3HCl) is characterized by a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-(1H-imidazol-4-yl)piperidine dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H13N3 2*HCl
Molecular Weight187.67 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1971
Halogen ContentCl-containing
Nitrogen Atoms3

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