4-Bromo-3,5-difluorobenzenesulfonyl Chloride CAS 518057-63-1
| CAS No. | 518057-63-1 |
| Molecular Formula | C6H2BrClF2O2S |
| Molecular Weight | 291.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-Bromo-3,5-difluorobenzenesulfonyl Chloride (CAS 518057-63-1), a certified reference material (molecular formula C6H2BrClF2O2S, MW 291.50 g/mol) for analytical method development and quality control.
4-Bromo-3,5-difluorobenzenesulfonyl Chloride (C6H2BrClF2O2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 4-Bromo-3,5-difluorobenzenesulfonyl Chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H2BrClF2O2S |
| Molecular Weight | 291.50 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl/Br-containing |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 4-Bromo-2,3-difluorobenzenesulfonyl chloride (CAS 1133123-00-8)
- 3-Bromo-2,6-difluorobenzenesulfonyl chloride (CAS 1349708-71-9)
- 3-Bromo-4,5-difluorobenzenesulfonyl chloride (CAS 1349715-69-0)
- 2-Bromo-3,4-difluorobenzenesulfonyl chloride (CAS 1349717-41-4)
- 3-Bromo-2,5-difluorobenzenesulfonyl chloride (CAS 1349717-49-2)
- 2-Bromo-3,5-difluorobenzenesulfonyl chloride (CAS 1349717-79-8)
- 6-Bromo-2,3-difluorobenzene-1-sulfonyl chloride (CAS 1349718-48-4)
- 2-Bromo-3,6-difluorobenzenesulfonyl chloride (CAS 1349718-72-4)
Recommended Standards
- 4-Bromo-2,6-difluorobenzenesulfonyl chloride (CAS 874804-21-4)
- 5-Bromo-2,4-difluorobenzene-1-sulfonyl chloride (CAS 287172-61-6)
- 3-Bromo-2,4-difluorobenzene-1-sulfonyl chloride (CAS 874804-10-1)
- 6-Bromo-4-(chloromethyl)-5-fluorophthalazin-1(2H)-one (CAS 2836223-99-3)
- 1-Ethynyl-4-(4-propylcyclohexyl)benzene (CAS 167858-58-4)
- Methyl 2-amino-3-(3-fluoro-4-hydroxyphenyl)propanoate hydrochloride (CAS 69978-78-5)
- Ethyl 4-(3-bromo-4-fluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 312632-07-8)
- Tetracosamethyl-cyclododecasiloxane (CAS 18919-94-3)
- Ethyl 5-amino-1-(3-nitrophenyl)-1h-1,2,3-triazole-4-carboxylate (CAS 123419-05-6)
- Potassium trifluoro(hex-1-yn-1-yl)borate (CAS 244301-59-5)
- 3-((2-(Tert-butyl)-5-methylphenoxy)methyl)-4-methoxybenzaldehyde (CAS 832737-62-9)
- Lemborexant impurity 13 (CAS CATO-C4X-304213)
- 4-((2-Oxo-5-(trifluoromethyl)pyridin-1(2H)-yl)methyl)benzoic acid (CAS 339024-98-5)
- Neuropeptide Y (2-36), amide, porcine (CAS 102961-52-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com