5-(2-Hydroxyphenyl)-2,4-dihydro-3h-pyrazol-3-one CAS 5186-66-3
| CAS No. | 5186-66-3 |
| Molecular Formula | C9H8N2O2 |
| Molecular Weight | 176.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 5-(2-Hydroxyphenyl)-2,4-dihydro-3h-pyrazol-3-one (CAS 5186-66-3), a certified reference material (molecular formula C9H8N2O2, MW 176.17 g/mol) for analytical method development and quality control.
The molecular framework of 5-(2-Hydroxyphenyl)-2,4-dihydro-3h-pyrazol-3-one (C9H8N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H8N2O2 |
| Molecular Weight | 176.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
Related Hydroxyphenyl Standards
- Methyl 3-(4-hydroxyphenyl)propiolate (CAS 136634-54-3)
- Methyl 3-(3-hydroxyphenyl)propiolate (CAS 1890847-27-4)
- 2-(2-Hydroxyphenyl)-1H-imidazol-4(5H)-one (CAS 88220-47-7)
- 4-(4-Hydroxyphenyl)-1H-imidazol-2(3H)-one (CAS 944916-40-9)
- Methyl 3-(2-hydroxyphenyl)propiolate (CAS 425686-45-9)
- n-(4-Hydroxyphenyl)-n-methylprop-2-ynamide (CAS 1042536-61-7)
- 5-(4-Hydroxyphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 942-69-8)
- 5-(4-Hydroxyphenyl)isoxazol-3-ol (CAS 76170-13-3)
Recommended Standards
- 5-(1-Methyl-1h-pyrazol-4-yl)furan-2-carbaldehyde (CAS 916235-17-1)
- 5-(4-Methyl-1H-imidazol-5-yl)furan-2-carbaldehyde (CAS 929003-85-0)
- 5-(1H)Indazole carboxylic acid methyl ester (CAS 473416-12-5)
- 5-(4-Methylphenyl)-3H-1,3,4-oxadiazol-2-one (CAS 83725-78-4)
- 4-(5-Oxazolyl)benzoic Acid (CAS 250161-45-6)
- 4-Bromo-N-methoxy-N-methylbenzene-1-sulfonamide (CAS 1250139-60-6)
- 3-((3-Nitropyridin-2-yl)amino)tetrahydrothiophene 1,1-dioxide (CAS 874640-48-9)
- 2,4,5-Trichloro-N-{[3-(4-methoxyphenyl)-1,2-oxazol-5-yl]methyl}benzene-1-sulfonamide (CAS 339016-97-6)
- Relugolix Impurity 44 (CAS CATO-C4X-242944)
- tert-Butyl 7-benzyl-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate (CAS 227940-71-8)
- 2-Cyclopropoxy-6-isopropylbenzamide (CAS 1243389-38-9)
- 3-Hydroxynaphthalene-1-sulfonic acid (CAS 6357-85-3)
- 4-(3-Chlorophenyl)tetrahydro-2H-pyran-4-carbaldehyde (CAS 902836-60-6)
- [a-Glu](Side chain transposition)- Semaglutide (CAS CATO-C4X-2226111)
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