5-Cyanothiophene-2-sulfonamide CAS 519055-65-3
| CAS No. | 519055-65-3 |
| Molecular Formula | C5H4N2O2S2 |
| Molecular Weight | 188.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-Cyanothiophene-2-sulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-Cyanothiophene-2-sulfonamide (CAS 519055-65-3), molecular formula C5H4N2O2S2 and molecular weight 188.23 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Cyanothiophene-2-sulfonamide (C5H4N2O2S2) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C5H4N2O2S2 |
| Molecular Weight | 188.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1984 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Cyanothiophene Standards
- 3-Cyanothiophene-2-sulfonamide (CAS 107142-12-1)
- 5-Cyanothiophene-3-sulfonamide (CAS 2657625-52-8)
- Ethyl 4-cyanothiophene-2-carboxylate (CAS 944901-15-9)
- Ethyl 5-cyanothiophene-2-carboxylate (CAS 67808-35-9)
- 4-Cyanothiophene-3-sulfonyl chloride (CAS 112472-37-4)
- 5-cyanothiophene-2-sulfonyl chloride (CAS 1803598-97-1)
- 5-Cyanothiophene-3-sulfonyl chloride (CAS 1934889-28-7)
- Methyl 2-cyanothiophene-3-carboxylate (CAS 67808-30-4)
Recommended Standards
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- N-(sec-butyl)tetrahydro-2H-pyran-4-amine (CAS 1154893-28-3)
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