1-(4-Chlorophenyl)-3-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)thiourea CAS 51944-21-9
| CAS No. | 51944-21-9 |
| Molecular Formula | C18H17ClN4OS |
| Molecular Weight | 372.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-Chlorophenyl)-3-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)thiourea.
1-(4-Chlorophenyl)-3-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)thiourea (CAS 51944-21-9) is a high-purity analytical reference standard with the molecular formula C18H17ClN4OS and a molecular weight of 372.87 g/mol.
The molecular framework of 1-(4-Chlorophenyl)-3-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)thiourea (C18H17ClN4OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(4-Chlorophenyl)-3-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)thiourea under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H17ClN4OS |
| Molecular Weight | 372.87 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- {5-[(2-chlorophenyl)sulfanyl]-1-methyl-3-phenyl-1H-pyrazol-4-yl}methyl acetate (CAS 318289-52-0)
- 1-[2-(4-Chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl N-phenylcarbamate (CAS 439111-31-6)
- 5-(2-Chlorophenyl)-4-((4-propoxybenzylidene)amino)-4H-1,2,4-triazole-3-thiol (CAS 478254-42-1)
- Ethyl 4-(2-chlorophenyl)-6-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 300571-30-6)
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- 4-Chlorophenyl 8-methyl-4H-thieno[3,2-c]thiochromene-2-carboxylate (CAS 478032-64-3)
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Recommended Standards
- 1-(5-Chloro-2-methylphenyl)-5-methyl-N-(2-(methylthio)phenyl)-1H-1,2,3-triazole-4-carboxamide (CAS 904817-46-5)
- N4-(6-(4-Chlorophenyl)pyridazin-3-yl)-[1,1'-biphenyl]-4,4'-diamine (CAS 901773-91-9)
- N-(4-Chlorophenyl)-6-methyl-2-phenylquinoline-4-carboxamide (CAS 337501-79-8)
- 2-(3-Chlorobenzenesulfonyl)-1,1-diphenylethan-1-ol (CAS 252026-35-0)
- (6-Chloro-5-(difluoromethyl)-3-methylpyridin-2-yl)methanol (CAS 1805379-01-4)
- (6-methyl[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)acetic acid (CAS 1160245-80-6)
- Licorisoflavan I (CAS 2444736-45-0)
- Ethyl 2-(2,5-dichlorophenyl)sulfanylacetate (CAS 1039844-00-2)
- 3-Amino-4-(4-chlorophenyl)-6-phenyl-N-(2-(trifluoromethyl)phenyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 337489-03-9)
- (S)-2-(4-methoxyphenyl)-5-(pyrrolidin-3-yl)-1,3,4-oxadiazole (CAS 1234684-70-8)
- 5-Chloro-2-(difluoromethoxy)benzoic acid (CAS 773869-44-6)
- Ethyl 3-methyl-5,6-dihydroimidazo[2,1-b]thiazole-2-carboxylate hydrochloride (CAS 34467-12-4)
- 6-(4-Fluorophenyl)-3-methylimidazo[2,1-b][1,3]thiazole-2-carboxylic acid (CAS 951908-85-3)
- HA Peptide (CAS 92000-76-5)
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