2-[2-[2-(2-Chloroethoxy)ethoxy]ethoxy]ethanol CAS 5197-66-0
| CAS No. | 5197-66-0 |
| Molecular Formula | C8H17ClO4 |
| Molecular Weight | 212.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-[2-[2-(2-Chloroethoxy)ethoxy]ethoxy]ethanol (CAS 5197-66-0), molecular formula C8H17ClO4 and molecular weight 212.67 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-[2-[2-(2-Chloroethoxy)ethoxy]ethoxy]ethanol (C8H17ClO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-[2-[2-(2-Chloroethoxy)ethoxy]ethoxy]ethanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H17ClO4 |
| Molecular Weight | 212.67 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
Related Chloroethoxy Standards
- 6-(2-Chloroethoxy)benzofuran-3(2H)-one (CAS 124627-69-6)
- N-(4-(2-chloroethoxy)phenyl)acetamide (CAS 36616-28-1)
- 4-(2-Chloroethoxy)-3-methoxybenzonitrile (CAS 1094313-50-4)
- 1-(4-(2-Chloroethoxy)-2-hydroxyphenyl)ethanone (CAS 109661-96-3)
- 4-(2-Chloroethoxy)-3-methoxybenzaldehyde (CAS 204915-71-9)
- 2-(2-Chloroethoxy)-4,6-dimethylnicotinonitrile (CAS 1053658-92-6)
- ((2-(2-Chloroethoxy)ethoxy)methyl)benzene (CAS 64352-98-3)
- 1-(2-Chloroethoxy)-2-isopropoxybenzene (CAS 915921-87-8)
Recommended Standards
- 2-(tert-Butyl)phenyl carbonochloridate (CAS 203984-34-3)
- 2-Butoxy-5-chlorobenzaldehyde (CAS 27590-76-7)
- 2-(4-Methoxyphenyl)-2-methylpropanoyl chloride (CAS 40919-14-0)
- 2-chloro-1-(4-ethoxyphenyl)propan-1-one (CAS 790270-99-4)
- 4-hydroxy-6,8-dimethoxyquinoline-3-carboxylic acid (CAS 874498-79-0)
- Tert-butyl ((1S,2R)-2-(aminomethyl)cyclohexyl)carbamate (CAS 1821775-80-7)
- 2-(2-Chlorophenyl)-1-(5-methylthiophen-3-yl)ethan-1-one (CAS 1497454-41-7)
- 5-(piperidin-1-ylmethyl)-1,2-oxazole-3-carboxylic acid hydrochloride (CAS 1803605-11-9)
- 1-Bromo-2-(tert-butoxymethyl)-3-methylbutane (CAS 1496966-83-6)
- 3-Ethyl-1-(4-hydroxycyclohexyl)urea (CAS 956711-41-4)
- 3-(2-(Methylthio)ethyl)imidazo[1,2-c]quinazolin-2(3H)-one (CAS 61381-34-8)
- (4-((4-Allyl-2-methoxyphenoxy)methyl)phenyl)methanamine (CAS 866039-46-5)
- 2,4-Dimethyl-3'-(4-methylpiperazinomethyl) benzophenone (CAS 898788-72-2)
- Peptide 436 (CAS CATO-CPTD788436)
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