Clomiphene Impurity 2 HCl CAS 52047-56-0
| CAS No. | 52047-56-0 |
| Molecular Formula | C19H23NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 333.86 g/mol gives Clomiphene Impurity 2 HCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Clomiphene Impurity 2 HCl (CAS 52047-56-0) is a high-purity analytical reference standard with the molecular formula C19H23NO2HCl and a molecular weight of 333.86 g/mol.
The molecular framework of Clomiphene Impurity 2 HCl (C19H23NO2HCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H23NO2 HCl |
| Molecular Weight | 333.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Clomiphene Standards
- Clomiphene-d5 Citrate (CAS 1217200-17-3)
- Clomiphene-d5 N-Oxide (CAS 1346606-55-0)
- trans-Clomiphene-d5 HCl (CAS 14158-65-7 (unlabelled))
- Clomiphene Impurity 9 (CAS 14770-94-6)
- cis-Clomiphene (CAS 15690-55-8)
- trans-Clomiphene (CAS 15690-57-0)
- Clomiphene Citrate (CAS 50-41-9)
- Clomiphene Impurity 1 (CAS 73404-00-9)
Recommended Standards
- (2E)-1-(2,4-Dimethoxyphenyl)-3-(3-methoxyphenyl)prop-2-en-1-one (CAS 1663469-39-3)
- 4-Bromo-β-hydroxybenzenepropanenitrile (CAS 65984-59-0)
- N-((11bS)-2,6-Bis(trifluoromethyl)-4-(((trifluoromethyl)sulfonyl)imino)-4l5-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl)-1,1,1-trifluoromethanesulfonamide (CAS 2757103-43-6)
- Methyl 3-(4-(aminomethyl)phenyl)propanoate (CAS 100511-78-2)
- 1-(3-Chloroquinolin-6-yl)ethan-1-one (CAS 1635407-48-5)
- 2,3-Dimethoxy-10-methylacridin-9(10H)-one (CAS 25379-17-3)
- 4-(Piperidin-4-yl)oxazolidin-2-one hydrochloride (CAS 2137775-16-5)
- 5-Iodo-4-(trifluoromethyl)pyrimidin-2-amine (CAS 1823882-28-5)
- 1-(tert-Butyl)-3-phenylisobenzofuran (CAS 52540-38-2)
- Semaglutide impurity 48 (CAS CATO-C4X-222648)
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