cis-4’-Hydroxy CCNU Lomustine CAS 52049-26-0
| CAS No. | 52049-26-0 |
| Molecular Formula | C9H16ClN3O3 |
| Molecular Weight | 249.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
cis-4’-Hydroxy CCNU Lomustine (C9H16ClN3O3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
cis-4’-Hydroxy CCNU Lomustine (CAS 52049-26-0) is a high-purity analytical reference standard with the molecular formula C9H16ClN3O3 and a molecular weight of 249.69 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures cis-4’-Hydroxy CCNU Lomustine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H16ClN3O3 |
| Molecular Weight | 249.69 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related cis Standards
- trans-4-Hydroxy lomustine (CAS 56239-24-8)
- 284487-60-1 3-Hydroxy(2,2,3,4,4-~2~H_5_)tetradecanoic acid DTXSID20584034 (CAS 284487-60-1)
- 2-Hydroxy-N-octylbenzamide (CAS 109972-90-9)
- N-(2-Hydroxy-1-methyl-2-phenylethyl)-N,3-dimethylbutanamide (CAS 1280520-91-3)
- 3-(2-Hydroxy-ethoxymethyl)-piperidine-1-carboxylic acid tert-butyl ester (CAS 1353987-71-9)
- 3-Hydroxy-5-iodobenzyl alcohol (CAS 50765-23-6)
- 5-Hydroxy-2-iodobenzyl alcohol (CAS 915707-73-2)
- 1-(3-hydroxyÂphenylÂ)-1-methoxyÂ-1-(2-thiazolylÂ)-propanÂe (CAS 129424-07-3)
Recommended Standards
- 8-(2-Chloroacetyl)-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one (CAS 847744-24-5)
- Ethyl 2-(3-chloroisoquinolin-1-yl)acetate (CAS 611235-27-9)
- 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-7-carboxylic acid (CAS 676470-14-7)
- ethyl 2-chloro-4-methylquinoline-3-carboxylate (CAS 251902-62-2)
- 1-[2-(4-Chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethyl N-phenylcarbamate (CAS 439111-31-6)
- 2-(1H-Benzo[d]imidazol-2-yl)ethyl thiazole-4-carboxylate (CAS 189438-52-6)
- tert-Butyl N-{[(2,3-dihydro-1H-inden-5-yl)carbamoyl]methyl}carbamate (CAS 1192998-98-3)
- (3S,3AR,6S,6aR)-3,6-Diazido-hexahydrofuro[3,2-b]furan (CAS 76753-09-8)
- 51666-29-6 benzyl-(3-bromo-1-methyl-propyl)-ether (CAS 51666-29-6)
- (1E)-1-(4-Hydroxyphenyl)ethanone Oxime (CAS 198712-64-0)
- N-cyclohexyl-4-(difluoromethoxy)aniline (CAS 1036451-20-3)
- 1-Oxaspiro[5.5]Undecan-4-ol (CAS 855398-42-4)
- (2R,3S,4S,5R,6S)-2-(acetoxymethyl)-4-(allyloxy)-6-(4-methoxyphenoxy)tetrahydro-2H-pyran-3,5-diyl diacetate (CAS 343254-39-7)
- Semaglutide impurity 01 (CAS 1998701-31-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com