2-Iodo-5-methylbenzoyl chloride CAS 52107-96-7
| CAS No. | 52107-96-7 |
| Molecular Formula | C8H6ClIO |
| Molecular Weight | 280.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Iodo-5-methylbenzoyl chloride is closely related to a hydroxyl group, an ether linkage, chlorine/iodine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Iodo-5-methylbenzoyl chloride (CAS 52107-96-7), molecular formula C8H6ClIO and molecular weight 280.49 g/mol, is a CATO reference standard with documented purity and traceability.
2-Iodo-5-methylbenzoyl chloride (C8H6ClIO) contains a hydroxyl group, an ether linkage, chlorine/iodine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6ClIO |
| Molecular Weight | 280.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl/I-containing |
Related Iodo Standards
- 5-Iodo-2-methylbenzoyl chloride (CAS 108440-70-6)
- 2-Iodo-4-methylbenzoyl chloride (CAS 52107-97-8)
- 3-Iodo-2-methylbenzoyl chloride (CAS 52107-91-2)
- 3-Iodo-5-methylbenzoyl chloride (CAS 52107-95-6)
- 52107-98-9 3-Iodo-4-methylbenzoyl chloride MFCD17015562 (CAS 52107-98-9)
- 2-Iodo-6-Chloropurine (CAS 18552-90-4)
- 4-Iodo-1-methyl-5-(trimethylsilyl)-1H-pyrazole (CAS 92525-11-6)
- 6-iodo-2,3-dimethyl-2H-indazole (CAS 1234616-58-0)
Recommended Standards
- 3-Benzyloxy-2-chloro-6-fluorophenylboronic acid (CAS 957062-67-8)
- 2-Chloro-2’-iodoacetophenone (CAS 4209-03-4)
- 3-Chloro-4-(4'-fluorobenzyloxy)phenylboronic acid (CAS 849062-39-1)
- 2-Chloro-1-(4-iodophenyl)ethan-1-one (CAS 4209-04-5)
- 2-(((4-Bromophenyl)imino)methyl)phenol (CAS 886-34-0)
- N1,N1-dimethyl-N2-(5-(trifluoromethyl)pyridin-2-yl)ethane-1,2-diamine hydrochloride (CAS 1311279-47-6)
- Ethyl 4-(cyclohexylamino)-2-phenylpyrimidine-5-carboxylate (CAS 477854-66-3)
- FITC-β-Ala-Amyloid β-Protein (1-42) ammonium salt (CAS 1802087-77-9)
- N,N-Bis((S)-1-phenylethyl)dibenzo[d,f][1,3,2]dioxaphosphepin-6-amine (CAS 376355-58-7)
- 5-Bromo-2-cyclohexylamino-3-nitropyridine (CAS 1033202-38-8)
- 4-([1,1'-Biphenyl]-4-yl)-5-(methylsulfonyl)-1H-thieno[2,3-c]pyrazol-3-amine (CAS 1707571-31-0)
- N-((1-methyl-1H-pyrrol-2-yl)methyl)cycloheptanamine (CAS 880813-26-3)
- 4,6-Dimethoxybenzofuran-2-carbaldehyde (CAS 108639-48-1)
- Semaglutide（sodium salt） (CAS CATO-C4X-222619)
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