Lysine Impurity 1 DiHCl CAS 52123-30-5
| CAS No. | 52123-30-5 |
| Molecular Formula | C12H26N4O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Lysine Impurity 1 DiHCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Lysine Impurity 1 DiHCl (CAS 52123-30-5, C12H26N4O3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Lysine Impurity 1 DiHCl is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 310.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C12H26N4O3 2*HCl |
| Molecular Weight | 310.82 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Lysine Standards
- L-Lysine Hydrochloride (CAS 10098-89-2)
- D-Lysine dihydrochloride (CAS 10303-72-7)
- Lysine Impurity 10 HCl (CAS 104584-11-4)
- L-Lysine-13C6,15N2 Hydrochloride (CAS 1200447-00-2)
- L-lysine-6-<SUP>13</SUP>C dihydrochloride (CAS 1217466-44-8)
- Lysine Impurity 25 (CAS 121893-23-0)
- Lysine Impurity 16 TFA Salt (CAS 13184-13-9(free base))
- L-Lysine-d4 Methyl Ester Dihydrochloride (CAS 1331896-92-4)
Recommended Standards
- Enzalutamide Impurity 7 (CAS 1802242-47-2)
- Lurasidone Impurity 23 (CAS 186204-37-5)
- Triptorelin Impurity 6 (CAS CATO-C4X-18626)
- 1-(6-(Benzylamino)-2-methylpyridin-3-yl)ethanol (CAS 1355174-15-0)
- 3-(3-Chlorobenzoyl)pyridine (CAS 62247-00-1)
- Ethyl 2-((1R,5R)-5-hydroxycyclopent-2-en-1-yl)acetate (CAS 298181-33-6)
- 4-Fluoro-2-methyl-5-nitrophenol (CAS 122455-84-9)
- Val-Asp-Ala-Ala-Val-Leu-Glu-Lys-Leu-Glu-Ala-Gly (CAS CATO-CPTD788422)
- 2-(4-Bromophenyl)cyclohexanone (CAS 91720-92-2)
- Semaglutide impurity 36 (CAS CATO-C4X-222636)
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