N-(4-Fluorophenyl)-2-hydroxy-4-methylbenzamide CAS 521272-14-0

Purity 97%+In StockPharmaceutical Standards
CAS No.521272-14-0
Molecular FormulaC14H12FNO2
Molecular Weight245.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(4-Fluorophenyl)-2-hydroxy-4-methylbenzamide CAS 521272-14-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 245.25 g/mol gives N-(4-Fluorophenyl)-2-hydroxy-4-methylbenzamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies N-(4-Fluorophenyl)-2-hydroxy-4-methylbenzamide (CAS 521272-14-0), a certified reference material (molecular formula C14H12FNO2, MW 245.25 g/mol) for analytical method development and quality control.

N-(4-Fluorophenyl)-2-hydroxy-4-methylbenzamide (C14H12FNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(4-Fluorophenyl)-2-hydroxy-4-methylbenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H12FNO2
Molecular Weight245.25 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Halogen ContentF-containing
Nitrogen Atoms1

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