2-Chloroethyl 2-(4-chlorophenoxy)-2-methylpropanoate CAS 52161-12-3
| CAS No. | 52161-12-3 |
| Molecular Formula | C12H14Cl2O3 |
| Molecular Weight | 277.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-Chloroethyl 2-(4-chlorophenoxy)-2-methylpropanoate (CAS 52161-12-3) is a high-purity analytical reference standard with the molecular formula C12H14Cl2O3 and a molecular weight of 277.14 g/mol.
The molecular framework of 2-Chloroethyl 2-(4-chlorophenoxy)-2-methylpropanoate (C12H14Cl2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H14Cl2O3 |
| Molecular Weight | 277.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl-containing |
Related Chloroethyl Standards
- 3-(2-Chloroethyl)-2-((2-chloroethyl)amino)-4-hydroxy-1,3,2-oxazaphosphinane 2-oxide (CAS 50892-10-9)
- 2-(1-chloroethyl)-5-(2,4-dichlorophenyl)-1,3,4-oxadiazole (CAS 1156191-87-5)
- 2-(1-Chloroethyl)-5-(3,4-dichlorophenyl)-1,3,4-oxadiazole (CAS 1156946-42-7)
- 5-(1-Chloroethyl)-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole (CAS 923753-68-8)
- 2-(1-chloroethyl)-5-(3,4-dichlorophenyl)-1,3-oxazole (CAS 1094318-44-1)
- 2-(1-Chloroethyl)-5-(2,4-dichlorophenyl)-1,3-oxazole (CAS 1094382-55-4)
- 4-(2-Chloroethyl)-N-(2-methoxyethyl)benzenesulfonamide (CAS 1018334-05-8)
- 4-(2-Chloroethyl)-N,N-diethylbenzenesulfonamide (CAS 1018537-40-0)
Recommended Standards
- 2,4-D sec-butyl ester (CAS 94-79-1)
- 3-(Bromomethyl)-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide (CAS 848187-60-0)
- 2-(4-Bromopyridin-2-yl)isothiazolidine 1,1-dioxide (CAS 1597022-64-4)
- 5-Bromoindoline-6-sulfonamide (CAS 2066546-05-0)
- cis-Dichloroplatinum,diTributylphosphanium (CAS 15390-92-8)
- 4-([1,1'-Biphenyl]-4-yl)-5-(methylsulfonyl)-1H-thieno[2,3-c]pyrazol-3-amine (CAS 1707571-31-0)
- 3-Fluoro-4-methylbenzyl Alcohol (CAS 192702-79-7)
- 3-chloro-1,2,4-benzotriazine (CAS 91669-21-5)
- n-(Tert-butyl)-4-ureidobenzamide (CAS 1209676-36-7)
- 2-(Difluoromethyl)-6-nitropyridine-3-carbonyl chloride (CAS 1805919-15-6)
- 7-Chloro-N,N-dimethylquinolin-4-amine (CAS 22072-07-7)
- Ethyl 1-((5-chloro-2-nitrophenyl)sulfonyl)azetidine-3-carboxylate (CAS 866152-80-9)
- Tert-butyl (5-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)carbamate (CAS 1105675-61-3)
- Des-Ser34-Gly33Tirzepatide (CAS CATO-CPTD788941)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com