2-(2-Fluorophenyl)-5-methyloxazole-4-carbonyl chloride CAS 52169-88-7
| CAS No. | 52169-88-7 |
| Molecular Formula | C11H7ClFNO2 |
| Molecular Weight | 239.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 239.63 g/mol gives 2-(2-Fluorophenyl)-5-methyloxazole-4-carbonyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(2-Fluorophenyl)-5-methyloxazole-4-carbonyl chloride (CAS 52169-88-7), molecular formula C11H7ClFNO2 and molecular weight 239.63 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(2-Fluorophenyl)-5-methyloxazole-4-carbonyl chloride (C11H7ClFNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(2-Fluorophenyl)-5-methyloxazole-4-carbonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H7ClFNO2 |
| Molecular Weight | 239.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Fluorophenyl Standards
- 2-(3-Fluorophenyl)-5-methyloxazole-4-carbonyl chloride (CAS 61152-05-4)
- 2-(4-Fluorophenyl)-5-methyloxazole-4-carbonyl chloride (CAS 61152-06-5)
- 3-(4-Fluorophenyl)-5-methylisoxazole-4-carbonyl chloride (CAS 465514-05-0)
- 2-(2-((4-Fluorophenyl)thio)ethyl)piperidine (CAS 1247061-41-1)
- 4-(2-Fluorophenyl)piperazine-1-carbothioamide (CAS 1178728-47-6)
- 4-(4-Fluorophenyl)piperazine-1-carbothioamide (CAS 25565-70-2)
- Ethyl 3-{[2-(4-fluorophenyl)ethyl]amino}propanoate (CAS 1099610-28-2)
- Methyl 3-{[2-(4-fluorophenyl)ethyl]amino}butanoate (CAS 1153450-62-4)
Recommended Standards
- 3-(2-Chloro-5-fluoropyrimidin-4-yloxy)-phenylamine (CAS 1643967-64-9)
- 1-(2-Chloro-6-fluorobenzyl)-1H-1,2,3-triazole-4-carbaldehyde (CAS 1478534-71-2)
- 2-(4-Aminophenyl)-4-chloro-5-fluoropyridazin-3(2H)-one (CAS 89593-79-3)
- 1-(3-Chloro-4-fluorophenyl)-1H-imidazole-4-carboxamide (CAS 1427014-72-9)
- (S)-5-fluoro-3-methylisobenzofuran-1(3H)-one (CAS 1803573-19-4)
- tert-Butyl 4-(bromomethyl)-5-methoxy-1H-benzo[d]imidazole-1-carboxylate (CAS 132873-84-8)
- 1-(4-(Aminomethyl)phenyl)propan-1-one (CAS 861103-05-1)
- 3-Methyl-1,4,5,6-tetrahydrocyclopenta[b]pyrrole-2-carbaldehyde (CAS 151051-66-0)
- 1022739-72-5 4-bromo-1-methyl-5-[(naphthalen-1-yloxy)methyl]-2-phenyl-2,3-dihydro-1H-pyrazol-3-one MS-8870 (CAS 1022739-72-5)
- 2-(3,4-Dimethoxyphenyl)-2-oxoacetaldehyde (CAS 15462-03-0)
- 5,7-Dichloro-1-indanone (CAS 448193-94-0)
- [R-[R*,R*-(Z)]]-α-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-1,2,5,7-tetrahydro-7-oxo-4H-Furo[3,4-d][1,3]thiazine-2-acetic AcidDISCONTINUED (CAS 75679-12-8)
- 3-(4H-1,2,4-Triazol-4-yl)-1H-pyrazole-4-carboxylic acid (CAS 1177347-16-8)
- Akt/SKG Substrate Peptide (CAS 276680-69-4)
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