7-Hydroxy-3-(4-methoxyphenyl)-4-methyl-2H-chromen-2-one CAS 5219-16-9
| CAS No. | 5219-16-9 |
| Molecular Formula | C17H14O4 |
| Molecular Weight | 282.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
7-Hydroxy-3-(4-methoxyphenyl)-4-methyl-2H-chromen-2-one (CAS 5219-16-9), molecular formula C17H14O4 and molecular weight 282.29 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 7-Hydroxy-3-(4-methoxyphenyl)-4-methyl-2H-chromen-2-one (C17H14O4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures 7-Hydroxy-3-(4-methoxyphenyl)-4-methyl-2H-chromen-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H14O4 |
| Molecular Weight | 282.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Hydroxy Standards
- (Z)-6-hydroxy-2-(2-methoxybenzylidene)-7-methylbenzofuran-3(2H)-one (CAS 1092298-15-1)
- (2Z)-6-Hydroxy-2-(3-methoxybenzylidene)-7-methyl-1-benzofuran-3(2H)-one (CAS 1092298-27-5)
- Methyl 4-hydroxy-2-phenyl-2H-chromene-3-carboxylate (CAS 129410-08-8)
- 1-(6-Hydroxy-2-(4-hydroxyphenyl)benzofuran-3-yl)propan-1-one (CAS 15824-26-7)
- (2E)-3-hydroxy-2-((4-methoxyphenyl)diazenyl)-1-phenylprop-2-en-1-one (CAS 77083-67-1)
- (Z)-6-hydroxy-2-(4-methoxybenzylidene)-7-methylbenzofuran-3(2H)-one (CAS 859663-74-4)
- 1-[2-Hydroxy-4,6-dimethoxy-3-(1-oxopropoxy)phenyl]-1-propanone (CAS 94190-88-2)
- 2-Hydroxy-2-(2-hydroxy-4,5-dimethylphenyl)-1H-indene-1,3(2H)-dione (CAS 71321-29-4)
Recommended Standards
- 7-Hydroxy-3-(2-methoxyphenyl)-2-methyl-4H-chromen-4-one (CAS 308087-55-0)
- 7-Hydroxy-4-(4-methoxyphenyl)-8-methyl-2h-chromen-2-one (CAS 370583-62-3)
- 7,8-Dimethoxyflavone (CAS 65548-54-1)
- 7-Methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one (CAS 20979-50-4)
- ethyl 6-fluorobenzofuran-3-carboxylate (CAS 863250-72-0)
- (4-Chlorophenyl)(prop-2-yn-1-yl)sulfane (CAS 17277-23-5)
- 5-Chloro-3-hydroxyquinazoline-2,4(1H,3H)-dione (CAS 824983-79-1)
- 3-Isobutyramido-2,2,3-trimethylbutanoic acid (CAS 1492838-80-8)
- tert-Butyl (3-(4-bromo-1H-pyrazol-1-yl)bicyclo[1.1.1]pentan-1-yl)carbamate (CAS 2529550-24-9)
- N1-butyl-N1-methylbenzene-1,2-diamine (CAS 1016727-11-9)
- 2-(2-Bromo-5-methylphenyl)propan-2-ol (CAS 1393477-32-1)
- {[2-(3-aminopropoxy)ethoxy]methyl}benzene (CAS 1443979-55-2)
- Emedastine EP Impurity C DiHCl (CAS 122423-32-9 (free base))
- Protein Kinase C (alpha) Peptide (CAS 159939-84-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com