5-Chloro-4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-2-methoxybenzoic acid CAS 52245-01-9
| CAS No. | 52245-01-9 |
| Molecular Formula | C16H10ClNO5 |
| Molecular Weight | 331.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
5-Chloro-4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-2-methoxybenzoic acid (CAS 52245-01-9) is a high-purity analytical reference standard with the molecular formula C16H10ClNO5 and a molecular weight of 331.71 g/mol.
Structurally, 5-Chloro-4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-2-methoxybenzoic acid (C16H10ClNO5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 331.71 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H10ClNO5 |
| Molecular Weight | 331.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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- 2-Bromo-4-chloro-3-(trifluoromethyl)pyridine (CAS 1211541-07-9)
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- Desmopressin Impurity 32 (CAS CATO-C4X-221532)
- Acetyl Hexapeptide-39 (CAS 1382088-38-1)
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