2-(5-Fluoro-2-methyl-1-oxo-1H-inden-3-yl)acetic acid CAS 52251-76-0
| CAS No. | 52251-76-0 |
| Molecular Formula | C12H9FO3 |
| Molecular Weight | 220.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(5-Fluoro-2-methyl-1-oxo-1H-inden-3-yl)acetic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(5-Fluoro-2-methyl-1-oxo-1H-inden-3-yl)acetic acid (CAS 52251-76-0), molecular formula C12H9FO3 and molecular weight 220.20 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(5-Fluoro-2-methyl-1-oxo-1H-inden-3-yl)acetic acid (C12H9FO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(5-Fluoro-2-methyl-1-oxo-1H-inden-3-yl)acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9FO3 |
| Molecular Weight | 220.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | F-containing |
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Recommended Standards
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- Ethyl 2-ethoxy-1H-benzo[d]imidazole-7-carboxylate (CAS 577957-02-9)
- 4-(2-Methoxybenzyl)-1,4-diazepan-5-one (CAS 1220030-54-5)
- 2-(3-Phenylpropoxy)aniline hydrochloride (CAS 108715-56-6)
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- Cilastatin Impurity 28 (CAS CATO-C4X-196028)
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- Calcium-Like Peptide 3 (CAS 261969-05-5)
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