2-chloroimidazo[1,2-a]pyridine-3-carboxylic acid CAS 522604-25-7

Purity 97%+In StockPharmaceutical Standards
CAS No.522604-25-7
Molecular FormulaC8H13ClN2O2
Molecular Weight204.65 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-chloroimidazo[1,2-a]pyridine-3-carboxylic acid CAS 522604-25-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-chloroimidazo[1,2-a]pyridine-3-carboxylic acid.

CATO supplies 2-chloroimidazo[1,2-a]pyridine-3-carboxylic acid (CAS 522604-25-7), a certified reference material (molecular formula C8H13ClN2O2, MW 204.65 g/mol) for analytical method development and quality control.

2-chloroimidazo[1,2-a]pyridine-3-carboxylic acid (C8H13ClN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-chloroimidazo[1,2-a]pyridine-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H13ClN2O2
Molecular Weight204.65 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1984
Halogen ContentCl-containing
Nitrogen Atoms2

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