2-Fluoro-4-sulfamoylbenzene-1-sulfonyl chloride CAS 52295-72-4
| CAS No. | 52295-72-4 |
| Molecular Formula | C6H5ClFNO4S2 |
| Molecular Weight | 273.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 2-Fluoro-4-sulfamoylbenzene-1-sulfonyl chloride (CAS 52295-72-4), a certified reference material (molecular formula C6H5ClFNO4S2, MW 273.69 g/mol) for analytical method development and quality control.
The molecular framework of 2-Fluoro-4-sulfamoylbenzene-1-sulfonyl chloride (C6H5ClFNO4S2) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 2-Fluoro-4-sulfamoylbenzene-1-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5ClFNO4S2 |
| Molecular Weight | 273.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
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Recommended Standards
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- 2,6-Diisopropyl-N,N-dimethylaniline (CAS 2909-77-5)
- (R)-2-Amino-1-(3-chloro-phenyl)-ethanol hydrochloride (CAS 169032-01-3)
- N1-(3-Amino-3-methylbutyl)-3-methylbutane-1,3-diamine (CAS 74568-96-0)
- Lipid X (CAS 86559-73-1)
- N-(2-Methoxyphenyl)-2,5-dimethylaniline (CAS 211292-60-3)
- (S)-6-Ethylchroman-4-amine (CAS 1228566-51-5)
- 2-[(1S)-1-Aminoethyl]-5-fluorophenol (CAS 1228542-70-8)
- Semaglutide impurity 29 (CAS 110990-08-4)
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