4-Amino-2.5-dimethoxy-N-phenylsulfonamide CAS 52298-44-9
| CAS No. | 52298-44-9 |
| Molecular Formula | C14H16N2O4S |
| Molecular Weight | 308.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4-Amino-2.5-dimethoxy-N-phenylsulfonamide (CAS 52298-44-9) is a high-purity analytical reference standard with the molecular formula C14H16N2O4S and a molecular weight of 308.35 g/mol.
The molecular framework of 4-Amino-2.5-dimethoxy-N-phenylsulfonamide (C14H16N2O4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H16N2O4S |
| Molecular Weight | 308.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Amino Standards
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- 3-(1-Isopentyl-3-propylpyrrolidin-3-yl)phenol 2-hydroxypropane-1,2,3-tricarboxylate (CAS 37627-59-1)
- N,N-Diethyl-2-((1-(o-tolyl)isoquinolin-3-yl)thio)ethanamine (CAS 89707-36-8)
- Flurbiprofen Impurity 163 (CAS 374936-00-2)
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- 3-Methylthiopropionamide (CAS 16536-93-9)
- [2-31]-Semaglutide C (x TFA Salt) (CAS CATO-C4X-2226118)
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