8-(Bis(2-chlorophenyl)methyl)-3-(pyrimidin-2-yl)-8-azabicyclo[3.2.1]octan-3-ol CAS 524019-25-8
| CAS No. | 524019-25-8 |
| Molecular Formula | C24H23Cl2N3O |
| Molecular Weight | 440.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 8-(Bis(2-chlorophenyl)methyl)-3-(pyrimidin-2-yl)-8-azabicyclo[3.2.1]octan-3-ol is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 8-(Bis(2-chlorophenyl)methyl)-3-(pyrimidin-2-yl)-8-azabicyclo[3.2.1]octan-3-ol (CAS 524019-25-8), a certified reference material (molecular formula C24H23Cl2N3O, MW 440.36 g/mol) for analytical method development and quality control.
The molecular framework of 8-(Bis(2-chlorophenyl)methyl)-3-(pyrimidin-2-yl)-8-azabicyclo[3.2.1]octan-3-ol (C24H23Cl2N3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 8-(Bis(2-chlorophenyl)methyl)-3-(pyrimidin-2-yl)-8-azabicyclo[3.2.1]octan-3-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H23Cl2N3O |
| Molecular Weight | 440.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Bis Standards
- 1-(4-Chlorophenyl)-2-((5-(3-chlorophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)ethan-1-one (CAS 874386-23-9)
- 6-(4-Chlorophenyl)-2-{[(6-chloropyridin-3-yl)methyl]sulfanyl}-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 674805-55-1)
- 3-(4-Chlorophenyl)-7-(5-(2,4-dichlorophenyl)furan-2-yl)pyrazolo[1,5-a]pyrimidine (CAS 439108-97-1)
- 4-[6-({[(4-chlorophenyl)methyl]sulfanyl}methyl)-2-phenylpyrimidin-4-yl]-2,6-dimethylmorpholine (CAS 866038-76-8)
- 1-[(4-Chlorophenyl)sulfanyl]-4-[(2,5-dichlorophenoxy)methyl]-2-nitrobenzene (CAS 477869-50-4)
- N-(1-(4-Chlorophenyl)ethyl)-2-((4-(4-fluorophenyl)-5-thioxo-4,5-dihydro-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 869866-06-8)
- 2-(3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl)-3-((tetrahydrofuran-2-yl)methyl)thiazolidin-4-one (CAS 380483-01-2)
- N-{4-[(2-{[(4-chlorophenyl)methyl]sulfanyl}-5,6,7,8-tetrahydroquinazolin-4-yl)oxy]phenyl}acetamide (CAS 339019-03-3)
Recommended Standards
- 3-((2,6-Dichlorobenzyl)sulfonyl)-N-(p-tolyl)thiophene-2-carboxamide (CAS 251097-78-6)
- 9,10-Dioxo-9,10-dihydroanthracene-1,2,5,8-tetrayl tetraacetate (CAS 2885-46-3)
- 2-(4-((4-Bromophenyl)sulfonyl)piperazin-1-yl)-N,N,6-trimethylpyrimidin-4-amine (CAS 946315-29-3)
- GP 2A (CAS 919077-81-9)
- Methyl 4-amino-3-bromo-2-hydroxybenzoate (CAS 1242268-24-1)
- N-(2,4-Dibromo-6-fluorophenyl)-N-methylthiourea (CAS 894211-42-8)
- 4-Bromo-3-fluoro-1-methylpyridin-2(1H)-one (CAS 2517593-01-8)
- 4-Acetamido-N-(2-aminoethyl)benzamide (CAS 56443-66-4)
- 4-Chloro-2,6-difluorophenylisothiocyanate (CAS 1823834-97-4)
- 4-Acetoxy-4-isopropylbenzophenone (CAS 890099-66-8)
- 4-Bromo-2-(difluoromethyl)phenol (CAS 939990-49-5)
- tert-Butyl 3-(4,4-difluoro-1-piperidyl)-azetidine-1-carboxylate (CAS 1257293-84-7)
- 2-(3-Hydroxypropyl)-1H-benzo[d]imidazole-6-carboxylic acid (CAS 313955-38-3)
- Semaglutide impurity 214 (CAS CATO-C4X-2226214)
Why CATO?
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