1-(4-Chlorophenyl)-3-hydroxy-1,4,5,6-tetrahydro-2H-indol-2-one CAS 52480-59-8

Description

The molecular framework of 1-(4-Chlorophenyl)-3-hydroxy-1,4,5,6-tetrahydro-2H-indol-2-one (C14H12ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

1-(4-Chlorophenyl)-3-hydroxy-1,4,5,6-tetrahydro-2H-indol-2-one (CAS 52480-59-8) is a high-purity analytical reference standard with the molecular formula C14H12ClNO2 and a molecular weight of 261.70 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(4-Chlorophenyl)-3-hydroxy-1,4,5,6-tetrahydro-2H-indol-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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