2,3,4,5,6-Pentamethylbenzene-1-sulfonyl chloride CAS 52499-94-2
| CAS No. | 52499-94-2 |
| Molecular Formula | C11H15ClO2S |
| Molecular Weight | 246.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,3,4,5,6-Pentamethylbenzene-1-sulfonyl chloride.
2,3,4,5,6-Pentamethylbenzene-1-sulfonyl chloride (CAS 52499-94-2) is a high-purity analytical reference standard with the molecular formula C11H15ClO2S and a molecular weight of 246.75 g/mol.
2,3,4,5,6-Pentamethylbenzene-1-sulfonyl chloride (C11H15ClO2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H15ClO2S |
| Molecular Weight | 246.75 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Pentamethylbenzene Standards
Recommended Standards
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- 4-Pentylbenzenesulfonyl chloride (CAS 73948-18-2)
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- 5-Tert-butyl-2-methylbenzene-1-sulfonyl chloride (CAS 63452-62-0)
- 5-Ethoxyfuro[3,4-b]pyridin-7(5H)-one (CAS 25230-60-8)
- (Cyclopropylmethyl)sulfamoyl Chloride (CAS 454219-12-6)
- 2-(5-Fluoro-2-methyl-1h-indol-3-yl)ethan-1-amine hydrochloride (CAS 1048343-51-6)
- 2-Bromo-1-fluoro-3-iodo-4-nitrobenzene (CAS 1805552-45-7)
- 1-Methyl-5-phenyl-1H-pyrrolo[3,2-b]pyridine-3-carboxylic acid (CAS 2106988-56-9)
- 2-Chloro-4-methoxybenzo[d]oxazole (CAS 1599561-87-1)
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- Neuropeptide GE (CAS 134748-04-2)
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