2-(3,5-Dichlorophenyl)acetonitrile CAS 52516-37-7
| CAS No. | 52516-37-7 |
| Molecular Formula | C8H5Cl2N |
| Molecular Weight | 186.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 186.04 g/mol gives 2-(3,5-Dichlorophenyl)acetonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(3,5-Dichlorophenyl)acetonitrile (CAS 52516-37-7) is a high-purity analytical reference standard with the molecular formula C8H5Cl2N and a molecular weight of 186.04 g/mol.
2-(3,5-Dichlorophenyl)acetonitrile (C8H5Cl2N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(3,5-Dichlorophenyl)acetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5Cl2N |
| Molecular Weight | 186.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Dichlorophenyl Standards
- 2-(2,3-Dichlorophenyl)acetonitrile (CAS 3218-45-9)
- 2-(2,6-Dichlorophenyl)acetonitrile (CAS 3215-64-3)
- 2-(3,5-Dichlorophenyl)propene (CAS 68575-36-0)
- 3-(2,3-Dichlorophenyl)-1-propene (CAS 951892-37-8)
- 3-(2,5-Dichlorophenyl)-1-propene (CAS 93794-95-7)
- 3-(3,5-Dichlorophenyl)-1-propene (CAS 75894-91-6)
- 2,4-Dichlorophenyl Cyanate (CAS 1601-46-3)
- 2,3-Dichlorophenyl Isocyanate (CAS 41195-90-8)
Recommended Standards
- 2,2-Dichloro-2-phenylacetonitrile (CAS 40626-45-7)
- 2,5-Dichloro-3-methylbenzonitrile (CAS 1807183-00-1)
- 2,4-Dichloro-5-methylbenzonitrile (CAS 33373-88-5)
- 3,4-Dichloro-5-methylbenzonitrile (CAS 1806346-88-2)
- (S)-4-methyl-1,1-diphenylpentan-2-amine (CAS 233772-40-2)
- 5-(Chloromethyl)-1-propyl-1H-1,2,3,4-tetrazole (CAS 848178-47-2)
- Pigment Orange 34 (Technical Grade) (CAS 15793-73-4)
- Methyl 3-nitro-4-(pyridin-2-ylthio)benzoate (CAS 346598-59-2)
- 2,5-Dioxopyrrolidin-1-yl 6-(2-(propan-2-ylidene)hydrazinyl)nicotinate (CAS 362522-50-7)
- 2-Chloro-N3-methylpyridine-3,4-diamine (CAS 1379240-45-5)
- Luteoreticulin (CAS 22388-89-2)
- N,N-Dimethyl-1,3-propanediamine (CAS 109-55-7)
- (2-Fluoro-5-methoxy-3-(trifluoromethyl)phenyl)methanol (CAS 1373921-03-9)
- Neuropeptide Y (13-36) (porcine) (CAS 113662-54-7)
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