2-(Phenylthio)-5-(trifluoromethyl)benzoic acid CAS 52548-96-6
| CAS No. | 52548-96-6 |
| Molecular Formula | C14H9F3O2S |
| Molecular Weight | 298.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 298.28 g/mol gives 2-(Phenylthio)-5-(trifluoromethyl)benzoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(Phenylthio)-5-(trifluoromethyl)benzoic acid (CAS 52548-96-6), molecular formula C14H9F3O2S and molecular weight 298.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(Phenylthio)-5-(trifluoromethyl)benzoic acid (C14H9F3O2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(Phenylthio)-5-(trifluoromethyl)benzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H9F3O2S |
| Molecular Weight | 298.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 3-((2-Methyl-6-phenylthieno[2,3-d]pyrimidin-4-yl)amino)benzoic acid hydrochloride (CAS 1052404-81-5)
- n-Methyl-1-(oxazol-5-yl)methanamine (CAS 1065073-40-6)
- 4-(4-Fluorophenyl)-5-(4-(pyrrolidin-1-ylsulfonyl)phenyl)-4H-1,2,4-triazole-3-thiol (CAS 917749-94-1)
- NoxA1ds (CAS 1435893-78-9)
- 1028067-91-5 7688AC C18H18N2O5S {[(1-Acetyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-amino}(phenyl)acetic acid (CAS 1028067-91-5)
- tert-Butyl (Z)-4'-((tert-butylsulfinyl)imino)-4'H,6'H-spiro[piperidine-4,5'-pyrrolo[1,2-b]pyrazole]-1-carboxylate (CAS 2843690-84-4)
- Proinsulin C-Peptide (55-89) (human) (CAS 11097-48-6)
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