6-Bromo-1H-benzo[de]isoquinoline-1,3(2H)-dione CAS 52559-36-1
| CAS No. | 52559-36-1 |
| Molecular Formula | C12H6BrNO2 |
| Molecular Weight | 276.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 6-Bromo-1H-benzo[de]isoquinoline-1,3(2H)-dione (CAS 52559-36-1), a certified reference material (molecular formula C12H6BrNO2, MW 276.09 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, 6-Bromo-1H-benzo[de]isoquinoline-1,3(2H)-dione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 276.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H6BrNO2 |
| Molecular Weight | 276.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 4-(Methylamino)tetrahydropyran Hydrochloride (CAS 392277-22-4)
- 4-(2-Oxopyrrolidin-1-yl)cyclohexanecarboxylic acid (CAS 820232-38-0)
- Rociletinib Impurity N1 (CAS 165897-63-2)
- N-Cyclopropyltetrahydro-2H-pyran-4-amine (CAS 211814-16-3)
- 3-Ethyl-2-propylquinoline (CAS 3290-24-2)
- 3-Fluoro-5-(hydroxymethyl)phenylboronic Acid Pinacol Ester (CAS 1400755-06-7)
- Tirzepatide Impurity 13 (CAS CATO-C4X-324013)
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