2-(4-Hydroxypyrimidin-5-yl)acetic acid CAS 5267-05-0
| CAS No. | 5267-05-0 |
| Molecular Formula | C6H6N2O3 |
| Molecular Weight | 154.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(4-Hydroxypyrimidin-5-yl)acetic acid (CAS 5267-05-0), a certified reference material (molecular formula C6H6N2O3, MW 154.12 g/mol) for analytical method development and quality control.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, 2-(4-Hydroxypyrimidin-5-yl)acetic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 154.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-Hydroxypyrimidin-5-yl)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6N2O3 |
| Molecular Weight | 154.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
Related Hydroxypyrimidin Standards
- (4-Ethyl-2-hydroxypyrimidin-5-yl)boronic acid (CAS 2225155-17-7)
- Methyl 2-(4-hydroxypyrimidin-2-yl)acetate (CAS 66621-49-6)
- Methyl 2-(5-hydroxypyrimidin-2-yl)acetate (CAS 948594-77-2)
- 2-Butyl-6-hydroxypyrimidin-4(3H)-one (CAS 60185-67-3)
- (4-Hydroxypyrimidin-5-yl)boronic acid (CAS 2225176-51-0)
- N-(2-Hydroxypyrimidin-5-yl)formamide (CAS 52767-98-3)
- 1-(2-Hydroxypyrimidin-5-yl)ethanone (CAS 87573-88-4)
- 2-Methyl-6-hydroxypyrimidin-4-one (CAS 1194-22-5)
Recommended Standards
- 2-(2-Oxopyrimidin-1(2H)-yl)acetic acid (CAS 95209-83-9)
- 2-(4-Methyl-5-oxofuran-2(5H)-ylidene)acetic acid (CAS 31934-89-1)
- 2-(2-Oxopyrazin-1(2H)-yl)acetic acid (CAS 42352-55-6)
- 2-(4-Oxo-1,4-dihydropyrimidin-2-yl)acetic acid (CAS 758632-69-8)
- 3-(2,5-Dioxo-pyrrolidin-1-yl)-propionic acid (CAS 5724-76-5)
- 2-(2-Fluorophenyl)-5-methyl-1,3-oxazole-4-carboxylic acid (CAS 61152-01-0)
- 2-(Benzo[d][1,3]dioxol-5-yl)-1-(7-(thiophen-2-yl)-1,4-thiazepan-4-yl)ethan-1-one (CAS 1705068-23-0)
- 2-(4-(Diphenylamino)phenyl)-9H-thioxanthen-9-one 10,10-dioxide (CAS 1623010-63-8)
- Met-Enkephalin-Arg-Phe (CAS 73024-95-0)
- 5-(4-(3,4,5-Trimethoxyphenyl)piperazin-1-yl)pyrrolidin-2-one (CAS 91703-26-3)
- 3-Methyl-2,3,4,9-tetrahydro-1H-carbazole-6-carboxylic acid (CAS 446829-41-0)
- (3,4-Difluoro-5-(isopentyloxy)phenyl)methanol (CAS 1443329-88-1)
- 4-Chloro-2-ethyl-1-fluorobenzene (CAS 1369889-05-3)
- Des-Gly34-Tirzepatide (CAS CATO-CPTD788940)
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