4-ethoxy-1,6-naphthyridine CAS 5268-41-7
| CAS No. | 5268-41-7 |
| Molecular Formula | C10H10N2O |
| Molecular Weight | 174.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-ethoxy-1,6-naphthyridine (CAS 5268-41-7), a certified reference material (molecular formula C10H10N2O, MW 174.20 g/mol) for analytical method development and quality control.
The molecular framework of 4-ethoxy-1,6-naphthyridine (C10H10N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10N2O |
| Molecular Weight | 174.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- 8-Methoxy-2-methyl-1-oxo-1,2-dihydrobenzo[b][1,6]naphthyridine-4-carbaldehyde (CAS 88752-83-4)
- 7-Methoxyquinoline-3-carboxaldehyde (CAS 72808-91-4)
- 2-Bromo-3-(difluoromethyl)-5-fluoro-4-nitropyridine (CAS 1805395-61-2)
- PF-06281355 (CAS 1435467-38-1)
- (4-((Methylsulfonyl)methyl)tetrahydro-2H-pyran-4-yl)methanamine (CAS 1423117-44-5)
- trans-1-Azaspiro[4.5]decan-8-ol (CAS 1202072-50-1)
- 59880-97-6 Chemotactic peptide F-Met-Leu-Phe L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)- N-Formyl-L-methionyl-L-leucyl-L-phenylalanine N-Formyl-Met-Leu-Phe N-Formylmethionine leucyl-phenylalanine fMLF fMLP (misnomer but widely used) (CAS 59880-97-6)
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