527-21-9 Fluoranil p-Benzoquinone, 2,3,5,6-tetrafluoro- (8CI) 2,5-Cyclohexadiene-1,4-dione, 2,3,5,6-tetrafluoro- (9CI) Tetrafluoro-p-benzoquinone EINECS 208-411-9 p-Fluoranil Fluoroanil NSC 264881 Tetrafluoro-1,4-benzoquinone Tetrafluoroquinone CAS 527-21-9
| CAS No. | 527-21-9 |
| Molecular Formula | C6F4O2 |
| Molecular Weight | 180.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 527-21-9 Fluoranil p-Benzoquinone, 2,3,5,6-tetrafluoro- (8CI) 2,5-Cyclohexadiene-1,4-dione, 2,3,5,6-tetrafluoro- (9CI) Tetrafluoro-p-benzoquinone EINECS 208-411-9 p-Fluoranil Fluoroanil NSC 264881 Tetrafluoro-1,4-benzoquinone Tetrafluoroquinone is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 180.06 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
527-21-9 Fluoranil p-Benzoquinone, 2,3,5,6-tetrafluoro- (8CI) 2,5-Cyclohexadiene-1,4-dione, 2,3,5,6-tetrafluoro- (9CI) Tetrafluoro-p-benzoquinone EINECS 208-411-9 p-Fluoranil Fluoroanil NSC 264881 Tetrafluoro-1,4-benzoquinone Tetrafluoroquinone (CAS 527-21-9) is a high-purity analytical reference standard with the molecular formula C6F4O2 and a molecular weight of 180.06 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6F4O2 |
| Molecular Weight | 180.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Recommended Standards
- 3,5-Dichloropyridine-4-thiol (CAS 33216-53-4)
- 7,7-Dichloro-6-methyl-3-azabicyclo[4.1.0]Heptane (CAS 1804129-11-0)
- 3,5-Dichloropyridine-2-thiol (CAS 41957-20-4)
- 2-Pentafluoroethyloxy-ethanol (CAS 91324-95-7)
- 3-(Furan-2-ylmethyl)-2-sulfanyl-3,4-dihydroquinazolin-4-one (CAS 333785-55-0)
- Cyclopentanecarboxylic acid (2-piperidin-2-yl-ethyl)-amide dihydrochloride (CAS 1185304-01-1)
- 3,4,5-Trimethoxybenzenethiol (CAS 16807-30-0)
- 8-Bromo-9-methyl-9H-purin-6-amine (CAS 56489-40-8)
- 6-Chloro-9-(4-methoxyphenyl)-9h-purine (CAS 21313-95-1)
- (4S,5R)-5-(6-Amino-9H-purin-9-yl)-4-hydroxy-2-methylenedihydrofuran-3(2H)-one (CAS 69995-90-0)
- 5-(Difluoromethyl)-3-iodo-4-methoxypicolinonitrile (CAS 1805489-26-2)
- 4-Chloro-3-nitrobenzenesulfonyl Chloride (CAS 97-08-5)
- 3-Bromo-4-hydroxy-2-(trifluoromethyl)pyridine (CAS 1227593-40-9)
- Tirzepatide Impurity 15 (CAS CATO-C4X-324015)
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