3-Methylpyrazine-2(1H)-thione CAS 5271-25-0
| CAS No. | 5271-25-0 |
| Molecular Formula | C5H6N2S |
| Molecular Weight | 126.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Methylpyrazine-2(1H)-thione.
CATO supplies 3-Methylpyrazine-2(1H)-thione (CAS 5271-25-0), a certified reference material (molecular formula C5H6N2S, MW 126.18 g/mol) for analytical method development and quality control.
The molecular framework of 3-Methylpyrazine-2(1H)-thione (C5H6N2S) is characterized by a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Methylpyrazine-2(1H)-thione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H6N2S |
| Molecular Weight | 126.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methylpyrazine Standards
- 5-Methylpyrazine-2,3(1H,4H)-dione (CAS 32493-61-1)
- 6-methylpyrazine-2-carbaldehyde (CAS 116758-01-1)
- 3-methylpyrazine-2-carbaldehyde (CAS 25513-93-3)
- 5-methylpyrazine-2-carbaldehyde (CAS 50866-30-3)
- 3-Methylpyrazine-2-methanol (CAS 160818-32-6)
- 3-Methylpyrazine-2,5-diamine (CAS 1823338-18-6)
- N2-Methylpyrazine-2,3-diamine (CAS 84996-40-7)
- 5-methylpyrazine-2,3-diamine (CAS 32493-82-6)
Recommended Standards
- 3-Aminopyridine-2-thiol (CAS 792850-88-5)
- 4-Amino-1,2-dihydropyridine-2-thione (CAS 59243-40-2)
- 3-Aminopyridine-2(1H)-thione (CAS 38240-21-0)
- 4-Amino-1,2-dihydropyridine-2-thione (CAS 775228-90-5)
- 4-[(2,4-Difluorophenoxy)methyl]benzoic acid (CAS 149288-45-9)
- 2-Amino-N-(1-(3-chlorophenyl)ethyl)-N-isopropylacetamide (CAS 1353964-00-7)
- (1S)-6,6'-Dibutyl[1,1'-binaphthalene]-2,2'-diol (CAS 1018066-09-5)
- 2-(Difluoromethyl)-3-iodo-4-nitropyridine-6-acetic acid (CAS 1807096-27-0)
- Ethyl 4,4-Dimethylpyrrolidine-3-carboxylate (CAS 1245649-01-7)
- Methyl (S)-N-Boc-morpholine-3-carboxylate (CAS 215917-98-9)
- 2-Fluoro-4-(4-(trifluoromethoxy)phenyl)pyridine (CAS 1261656-26-1)
- 2-(3-Chlorophenyl)-3,3,3-trifluoro-2-hydroxypropanoic acid (CAS 1507285-78-0)
- Methyl 3,4-dihydro-2h-1,4-benzoxazine-2-carboxylate hydrochloride (CAS 90922-33-1)
- Neuropeptide FF (CAS 99566-27-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com