4-Methyl-N-(pyridin-2-yl)benzenesulfonamide CAS 52776-76-8

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Methyl-N-(pyridin-2-yl)benzenesulfonamide.

4-Methyl-N-(pyridin-2-yl)benzenesulfonamide (CAS 52776-76-8) is a high-purity analytical reference standard with the molecular formula C12H12N2O2S and a molecular weight of 248.30 g/mol.

Structurally, 4-Methyl-N-(pyridin-2-yl)benzenesulfonamide (C12H12N2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 248.30 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-Methyl-N-(pyridin-2-yl)benzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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