Tenoxicam EP Impurity D CAS 52781-01-8
| CAS No. | 52781-01-8 |
| Molecular Formula | C8H9N3O2 |
| Molecular Weight | 179.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tenoxicam EP Impurity D.
CATO supplies Tenoxicam EP Impurity D (CAS 52781-01-8), a pharmacopoeial impurity reference standard (molecular formula C8H9N3O2, MW 179.18 g/mol) used for the identification and quantification of trace impurities in APIs.
Tenoxicam EP Impurity D (C8H9N3O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9N3O2 |
| Molecular Weight | 179.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 3 |
Related Tenoxicam Standards
Recommended Standards
- Uridine Impurity 11 (CAS 69251-45-2)
- 4-(2-Fluorophenoxy)butanenitrile (CAS 1016501-71-5)
- Acetyl Isoniazid (CAS 1078-38-2)
- 4-(3-Fluorophenoxy)butanenitrile (CAS 1016751-19-1)
- Pemafibrate Impurity 77 (CAS CATO-C4X-290377)
- Vortioxetine Impurity 60 (CAS 1049755-55-6)
- Stiripentol Impurity 13 (CAS CATO-C4X-322913)
- 4-Bromodihydrothiophen-3(2H)-one 1,1-dioxide (CAS 143654-18-6)
- Diethyl 4,4'-(thiocarbonylbis(azanediyl))dibenzoate (CAS 1429-24-9)
- 2-Hydroxy-8-methyl-4-oxo-N-propyl-4H-pyrido[1,2-a]pyrimidine-3-carboxamide (CAS 886895-88-1)
- Promethazine EP Impurity C (R-Isomer) (CAS CATO-C3D-262692)
- 1,3,5-Trimethyl-1,1,3,5,5-pentaphenyltrisiloxane (CAS 3390-61-2)
- 2-Methoxy-3-methyl-5-nitropyridine (CAS 89694-10-0)
- D-allo-Thr7-Semaglutide (CAS CATO-C4X-2226242)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com