7-Nitro-2,3-dihydro-1,4-benzodioxine-6-sulfonyl chloride CAS 5279-54-9
| CAS No. | 5279-54-9 |
| Molecular Formula | C8H6ClNO6S |
| Molecular Weight | 279.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
7-Nitro-2,3-dihydro-1,4-benzodioxine-6-sulfonyl chloride (CAS 5279-54-9), molecular formula C8H6ClNO6S and molecular weight 279.65 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 7-Nitro-2,3-dihydro-1,4-benzodioxine-6-sulfonyl chloride (C8H6ClNO6S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 279.65 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 7-Nitro-2,3-dihydro-1,4-benzodioxine-6-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6ClNO6S |
| Molecular Weight | 279.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Nitro Standards
- 1-(4-Nitro-5-(phenylthio)thiophen-2-yl)ethanone (CAS 90680-28-7)
- 3-Nitro Lidocaine (CAS 39942-49-9)
- 4-(4-Nitro-benzyl)-tetrahydro-pyran-4-carboxylic acid methyl ester (CAS 1229626-92-9)
- 2-Methyl-6-nitro-3-phenylquinolin-4-amine (CAS 828930-81-0)
- Ethyl 3-nitro-4-(piperazin-1-yl)benzoate (CAS 886631-29-4)
- 4-Nitro-N-(pyridin-2-yl)benzenesulfonamide (CAS 1028-11-1)
- 4-Nitro-N-pyridin-4-ylbenzenesulfonamide (CAS 15362-60-4)
- 4-Nitro-N-(pyridin-3-yl)benzenesulfonamide (CAS 326901-73-9)
Recommended Standards
- 4-Chloro-3-(methylsulfonyl)-5-nitrobenzoic acid (CAS 32548-10-0)
- Methyl 5-(chlorosulfonyl)-2-nitrobenzoate (CAS 2089314-98-5)
- 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-2-one (CAS 923143-11-7)
- N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N'-methylacrylohydrazide (CAS 338965-00-7)
- Bis(2-[(piperidin-4-yl)methoxy]pyridine-3-carbonitrile) trihydrochloride (CAS 2097893-65-5)
- (6-Bromo-4-iodopyridin-2-yl)methanamine (CAS 1393554-96-5)
- 3-Butyl-2-mercapto-3H-quinazolin-4-one (CAS 13906-07-5)
- 4-Ethyl-1-methyl-3-(pyridin-4-yl)-1h-pyrazol-5-amine (CAS 1156895-03-2)
- 2-((6-Methoxy-2-methylquinolin-4(1h)-ylidene)amino)ethan-1-ol (CAS 379255-84-2)
- N-[2-(4-Aminophenyl)ethyl]methanesulfonamide (CAS 24954-59-4)
- Spiro[azetidine-3,2'-benzo[h]chromen]-4'(3'H)-one (CAS 1263284-98-5)
- 2-chloro-4-nitrobenzene-1-thiol (CAS 36776-29-1)
- N-(2-Methoxyphenyl)-2-(8-methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetamide (CAS 732999-94-9)
- Semaglutide impurity 28 (CAS CATO-C4X-222628)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com