Ethyl 3-(4-bromophenyl)-2-methyl-3-oxopropanoate CAS 52884-49-8
| CAS No. | 52884-49-8 |
| Molecular Formula | C12H13BrO3 |
| Molecular Weight | 285.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ethyl 3-(4-bromophenyl)-2-methyl-3-oxopropanoate (C12H13BrO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Ethyl 3-(4-bromophenyl)-2-methyl-3-oxopropanoate (CAS 52884-49-8), a certified reference material (molecular formula C12H13BrO3, MW 285.13 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H13BrO3 |
| Molecular Weight | 285.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Br-containing |
Related Ethyl Standards
- 6-(4-Bromophenyl)-6-oxohexanoic acid (CAS 102862-52-2)
- 4-(4-Bromophenyl)tetrahydro-2H-pyran-4-carboxylic acid, 97% (CAS 1152567-60-6)
- 6-(4-Bromophenyl)-4-oxohexanoic acid (CAS 1263282-83-2)
- 3-[(3-bromophenyl)methyl]oxolane-3-carboxylic acid (CAS 1342633-06-0)
- 4-(2-Bromophenyl)tetrahydro-2h-pyran-4-carboxylic acid (CAS 1343422-38-7)
- 5-(4-Bromophenyl)-3-methyl-5-oxopentanoic acid (CAS 1343735-62-5)
- Ethyl 3-(4-bromophenyl)oxetane-3-carboxylate (CAS 1370035-61-2)
- Methyl 2-(3-(4-bromophenyl)oxetan-3-yl)acetate (CAS 1393585-24-4)
Recommended Standards
- Ethyl 3-(3-bromophenyl)-3-methyloxirane-2-carboxylate (CAS 81606-42-0)
- Ethyl 3-(4-bromophenyl)-3-methyloxirane-2-carboxylate (CAS 81606-33-9)
- Ethyl 2-(4-(2-bromoacetyl)phenyl)acetate (CAS 55453-49-1)
- Ethyl 3-bromo-2-oxo-4-phenylbutanoate (CAS 292858-05-0)
- 1,2-Benzenedicarboxylic acid, nonyl undecyl ester, branched and linear (CAS 111381-91-0)
- 2,5-Dichloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS 1269233-14-8)
- 3-[4-(methoxycarbonyl)-1,3-oxazol-5-yl]propanoic acid (CAS 41172-61-6)
- 3-Ethyl-3-phenyl-3H-indol-2-amine (CAS 61352-07-6)
- (2-Methyl-propane-1-sulfonyl)-acetonitrile (CAS 1154877-12-9)
- Methyl 5-fluoro-3-methylpicolinate (CAS 1346148-32-0)
- 4-((6-Chloropyrimidin-4-yl)oxy)aniline (CAS 105130-28-7)
- (3R,4S)-N-Boc-3,4-epoxy-L-proline (CAS 194737-56-9)
- 2-(4-Bromo-3-formylphenoxy)-5-fluorobenzonitrile (CAS 1353100-93-2)
- Semaglutide Impurity 160 (x TFA Salt) (CAS CATO-C4X-2226160)
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