4-(Isoquinolin-1-yl)benzoic acid CAS 52947-18-9
| CAS No. | 52947-18-9 |
| Molecular Formula | C16H11NO2 |
| Molecular Weight | 249.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(Isoquinolin-1-yl)benzoic acid (CAS 52947-18-9) is a high-purity analytical reference standard with the molecular formula C16H11NO2 and a molecular weight of 249.26 g/mol.
The molecular framework of 4-(Isoquinolin-1-yl)benzoic acid (C16H11NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 4-(Isoquinolin-1-yl)benzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H11NO2 |
| Molecular Weight | 249.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 1 |
Related Isoquinolin Standards
- 3-(Isoquinolin-1-yl)benzoic acid (CAS 1206969-87-0)
- 2-(Isoquinolin-1-yl)benzoic acid (CAS 95264-23-6)
- 1-(Isoquinolin-1-yl)-1-phenylethan-1-ol (CAS 5467-83-4)
- N-(Isoquinolin-4-yl)benzamide (CAS 681448-78-2)
- Isoquinolin-3-ylmethyl-phosphonic acid dimethyl ester (CAS 2097068-77-2)
- Isoquinolin-4-yl(m-tolyl)methanone (CAS 1187165-88-3)
- Isoquinolin-4-yl(p-tolyl)methanone (CAS 1187169-56-7)
- Isoquinolin-1-yl(p-tolyl)methanol (CAS 5467-96-9)
Recommended Standards
- 4-(5-Phenyloxazol-2-yl)benzaldehyde (CAS 61351-62-0)
- 4-(Phenylamino)naphthalene-1,2-dione (CAS 27828-56-4)
- 4-(2-Morpholino-2-oxoethoxy)benzaldehyde (CAS 30817-36-8)
- 4-(Quinolin-3-yl)benzoic acid (CAS 216059-94-8)
- 1-(Cyclohexanecarbonyl)-1H-1,2,4-triazole-5-carboxamide (CAS 62735-24-4)
- 1H,2H,3H-thieno[2,3-d]imidazol-2-one (CAS 71309-43-8)
- 4-(5-Trifluoromethyl-pyridin-2-yl)-benzoyl chloride (CAS 223128-27-6)
- 4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)butan-2-one (CAS 100818-32-4)
- 3-(6-Fluoropyridin-3-yl)phenol (CAS 1400975-00-9)
- 8-Chloro-3,3,11-trimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one (CAS 946387-35-5)
- 2-(1-Methyl-1h-pyrazol-5-yl)quinoline-4-carboxylic acid (CAS 925146-01-6)
- Ethyl 2-(4-(methylsulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)acetate (CAS 1710853-71-6)
- 5-Hydroxyisoquinoline-6-carboxylic acid (CAS 1332370-65-6)
- Amyloid Precursor Frameshift Mutant C-Terminal Peptide trifluoroacetate salt (CAS 189125-14-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com