2,4-Dichloro-N,N-dimethylpyrimidin-5-amine CAS 5298-50-0
| CAS No. | 5298-50-0 |
| Molecular Formula | C6H7Cl2N3 |
| Molecular Weight | 192.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2,4-Dichloro-N,N-dimethylpyrimidin-5-amine (CAS 5298-50-0), molecular formula C6H7Cl2N3 and molecular weight 192.05 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,4-Dichloro-N,N-dimethylpyrimidin-5-amine (C6H7Cl2N3) is characterized by a nitrile group, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 2,4-Dichloro-N,N-dimethylpyrimidin-5-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H7Cl2N3 |
| Molecular Weight | 192.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Dichloro Standards
- 4,6-Dichloro-N-ethylpyrimidin-2-amine (CAS 10371-48-9)
- 2,6-Dichloro-N,N-dimethylpyrimidin-4-amine (CAS 117077-93-7)
- 5,6-Dichloro-N,N-dimethylpyridazin-4-amine (CAS 17258-34-3)
- 3,5-Dichloro-N,N-dimethylpyrazin-2-amine (CAS 1935333-43-9)
- 5,6-Dichloro-N,N-dimethylpyrazin-2-amine (CAS 1936121-46-8)
- 2,4-Dichloro-6-isopropyl-1,3,5-triazine (CAS 30894-74-7)
- 2,6-dichloro-4-N-methylpyridine-3,4-diamine (CAS 914942-86-2)
- 2,6-Dichloro-5-ethylpyrimidin-4-amine (CAS 81316-68-9)
Recommended Standards
- 2-(Bromomethyl)-N,N-dimethyl-2-propenamide (CAS 911011-46-6)
- 2-(4,6-Dichloropyrimidin-2-yl)ethan-1-amine (CAS 933683-13-7)
- 2,6-Dichloro-N-ethylpyrimidin-4(3H)-imine (CAS 70958-39-3)
- 1-(4-bromo-1H-pyrrol-2-yl)ethanone (CAS 51333-64-3)
- n,n-Diethyl-4-(hydroxymethyl)benzenesulfonamide (CAS 15148-75-1)
- 4-(Difluoromethyl)-6-(hydroxymethyl)-5-iodopyridin-3-ol (CAS 1805452-63-4)
- tert-Butyl (S)-(1-methyl-2-oxopyrrolidin-3-yl)carbamate (CAS 92235-35-3)
- 5-propylthiophene-2-carbaldehyde (CAS 35250-76-1)
- 3-Carboxy-1-(4-sulfophenyl)-5-pyrazolone Sodium Salt (CAS 52126-51-9)
- (3-Fluoro-4-((tetrahydro-2H-pyran-4-yl)oxy)phenyl)methanamine (CAS 1247619-84-6)
- 2-(4-Bromomethylphenyl)-2-methylpropionic Acid Ethyl Ester (CAS 211105-00-9)
- 3-[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-thiazolyl]pyridine (CAS 1402165-88-1)
- Ixazomib Impurity 60 (CAS CATO-C4X-126760)
- Semaglutide Impurity 162 (x TFA Salt) (CAS CATO-C4X-2226162)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com