6-(Piperidin-1-ylmethyl)-6H-indolo[2,3-b]quinoxaline CAS 53003-21-7
| CAS No. | 53003-21-7 |
| Molecular Formula | C20H20N4 |
| Molecular Weight | 316.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-(Piperidin-1-ylmethyl)-6H-indolo[2,3-b]quinoxaline (CAS 53003-21-7) is a high-purity analytical reference standard with the molecular formula C20H20N4 and a molecular weight of 316.40 g/mol.
6-(Piperidin-1-ylmethyl)-6H-indolo[2,3-b]quinoxaline (C20H20N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-(Piperidin-1-ylmethyl)-6H-indolo[2,3-b]quinoxaline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H20N4 |
| Molecular Weight | 316.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 4 |
Related Piperidin Standards
- 2-Phenyl-4-(2-(piperidin-4-yl)ethyl)quinoline (CAS 77472-98-1)
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- 3-[3-(4-butyl-piperidin-1-yl)-propyl]-benzo[d]isothiazole (CAS 372197-81-4)
- 2-[(Piperidin-1-yl)carbonyl]-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1314080-45-9)
- (3-{[4-(Piperidin-1-ylcarbonyl)piperidin-1-yl]carbonyl}phenyl)amine (CAS 1243093-19-7)
- 6-(2-(Piperidin-1-yl)ethyl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purine (CAS 920503-18-0)
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Recommended Standards
- 6-(Methylthio)-N2-(4-phenylthiazol-2-yl)-1,3,5-triazine-2,4-diamine (CAS 88067-14-5)
- 6-Ethoxy-2-(4-phenylbuta-1,3-dien-1-yl)quinolin-4-amine (CAS 646068-84-0)
- 5,10-dihydro-3,7-dimethyl-10-phenyl-2,8-Phenazinediamine (CAS 63317-00-0)
- Benzo[d]thiazol-2-ylmethyl 2-(methylthio)nicotinate (CAS 473672-87-6)
- Galactinol (CAS 3687-64-7)
- 1-[3-(aminomethyl)phenyl]-N-methylmethanesulfonamide hydrochloride (CAS 1221723-71-2)
- Tert-butyl 8-oxooctahydroquinoline-1(2H)-carboxylate (CAS 1823795-15-8)
- (S)-5-bromo-7,8-difluoro-3-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine (CAS 2250039-90-6)
- 3-Bromo-2-(cyclopropylmethoxy)-5-fluoroaniline (CAS 1155956-29-8)
- 3-(2-Methylphenyl)-3-pyrrolidinol hydrochloride (CAS 91246-30-9)
- (2-(Sec-butyl)-6-(piperidin-3-yl)pyridin-4-yl)boronic acid (CAS 2225152-73-6)
- 3,5-Bis(3-methoxyphenyl)-4-methyl-1H-pyrazole (CAS 1159937-05-9)
- Diethyl n-isopropylsulfamide (CAS 1326758-90-0)
- (Tyr?)-C-Peptide (human) (CAS 57327-90-9)
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