2-(1,1,2,3,3,3-Hexafluoropropyl)tetrahydrofuran CAS 53005-42-8

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(1,1,2,3,3,3-Hexafluoropropyl)tetrahydrofuran.

CATO supplies 2-(1,1,2,3,3,3-Hexafluoropropyl)tetrahydrofuran (CAS 53005-42-8), a certified reference material (molecular formula C7H8F6O, MW 222.13 g/mol) for analytical method development and quality control.

Owing to a hydroxyl group, an ether linkage, fluorine substitution, 2-(1,1,2,3,3,3-Hexafluoropropyl)tetrahydrofuran is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 222.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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