1,4-Dihydro-2,6-Dimethyl-4-[O-(Trifluoromethyl)Phenyl]-3,5-Pyridinedicarboxylic Acid Dimethyl Ester CAS 53219-40-2
| CAS No. | 53219-40-2 |
| Molecular Formula | C18H18F3NO4 |
| Molecular Weight | 369.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1,4-Dihydro-2,6-Dimethyl-4-[O-(Trifluoromethyl)Phenyl]-3,5-Pyridinedicarboxylic Acid Dimethyl Ester is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1,4-Dihydro-2,6-Dimethyl-4-[O-(Trifluoromethyl)Phenyl]-3,5-Pyridinedicarboxylic Acid Dimethyl Ester (CAS 53219-40-2), molecular formula C18H18F3NO4 and molecular weight 369.34 g/mol, is a CATO reference standard with documented purity and traceability.
1,4-Dihydro-2,6-Dimethyl-4-[O-(Trifluoromethyl)Phenyl]-3,5-Pyridinedicarboxylic Acid Dimethyl Ester (C18H18F3NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1,4-Dihydro-2,6-Dimethyl-4-[O-(Trifluoromethyl)Phenyl]-3,5-Pyridinedicarboxylic Acid Dimethyl Ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H18F3NO4 |
| Molecular Weight | 369.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Dihydro Standards
- 8,14-Dihydro-14-methyl-11-(trifluoromethyl)-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one (CAS 747-91-1)
- 3-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione (CAS 1239986-50-5)
- Dihydro Fenofibrate-d6 (CAS 1189501-82-3)
- 2,2'-(2,3-Dihydro-1H-indene-4,6-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) (CAS 1218790-33-0)
- n-(5,6-Dihydro-4h-cyclopenta[d]thiazol-2-yl)-3-iodobenzamide (CAS 600136-84-3)
- 1-(2,3-Dihydro-1H-inden-5-yl)-4-(4-methoxyphenoxy)phthalazine (CAS 866133-82-6)
- (2E)-3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-[4-(4-fluorophenyl)piperazin-1-yl]prop-2-en-1-one (CAS 882081-82-5)
- 2,3-Dihydro-2-N-acetyl-1',2'-di-O-acetyl-biopterin-d3 (CAS 1346597-41-8)
Recommended Standards
- (2-((4-fluoro-3-(trifluoromethyl)phenyl)amino)-4-(pyridin-4-yl)thiazol-5-yl)methanol (CAS 929562-28-7)
- 2-((3-(4-Fluorophenyl)benzo[c]isoxazol-5-yl)methylene)-1H-indene-1,3(2H)-dione (CAS 685107-61-3)
- (S)-4-(4-Fluoro-2-nitrophenyl)-1-(tert-butoxy-carbonyl)piperazine-2-carboxylic acid (CAS 1786943-08-5)
- 2-((3-Cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl)thio)-N-(4-fluorophenyl)acetamide (CAS 445222-40-2)
- 4-(1-(4-Chlorophenoxy)ethyl)pyrimidin-2-amine (CAS 339021-08-8)
- 5-{[(2-chlorophenyl)methyl]sulfanyl}-3-(cyclohexylmethyl)-8,9-dimethoxy-2H,3H-imidazo[1,2-c]quinazolin-2-one (CAS 1024013-32-8)
- tert-Butyl (2R,4S)-2-methyl-4-(((methylsulfonyl)oxy)methyl)pyrrolidine-1-carboxylate (CAS 2824189-00-4)
- DL-Dihydro-Orotic Acid (CAS 155-54-4)
- 1-(Ethoxyethynyl)cyclopentan-1-ol (CAS 100144-59-0)
- N-(6-Ethoxy-3-(2-ethoxyethyl)benzo[d]thiazol-2(3H)-ylidene)cyclopropanecarboxamide (CAS 865174-36-3)
- {1-[amino(1-methyl-1H-pyrazol-4-yl)methyl]cyclobutyl}methanol dihydrochloride (CAS 1808436-98-7)
- Oxycodone Related Compound B CII (F1I028) (CAS 71539-52-1)
- 1-[(2,6-Difluorophenyl)methyl]-4-nitro-1h-pyrazole (CAS 1240567-86-5)
- D-Pro38-Tirzepatide (CAS CATO-CPTD788901)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com