5-Chloro-3-hydroxypyridin-2(1H)-one CAS 53233-89-9
| CAS No. | 53233-89-9 |
| Molecular Formula | C5H4ClNO2 |
| Molecular Weight | 145.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 5-Chloro-3-hydroxypyridin-2(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
5-Chloro-3-hydroxypyridin-2(1H)-one (CAS 53233-89-9) is a high-purity analytical reference standard with the molecular formula C5H4ClNO2 and a molecular weight of 145.54 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, 5-Chloro-3-hydroxypyridin-2(1H)-one is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 145.54 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C5H4ClNO2 |
| Molecular Weight | 145.54 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-Chloro-6-hydroxypyridin-2(1H)-one (CAS 103792-71-8)
- 3-Chloro-1H-pyrrole-2-carboxylic acid (CAS 1053658-09-5)
- 2-Chloro-3-hydroxypyridin-4(1H)-one (CAS 1204295-69-1)
- 2-Chloro-1-oxazol-2-yl-ethanone (CAS 1211536-43-4)
- 2-Chloro-1-oxazol-4-yl-ethanone (CAS 1216314-67-8)
- 5-Chloro-3-methyl-1,2-oxazole-4-carbaldehyde (CAS 1314901-77-3)
- 6-Chloro-3-hydroxypyridin-2(1H)-one (CAS 1420535-82-5)
- 2-Chloro-1-(oxazol-5-yl)ethan-1-one (CAS 1421314-19-3)
Recommended Standards
- 5-chloro-1H-pyrrole-2-carboxylic acid (CAS 27746-04-9)
- 6-Chloro-4-hydroxy-2(1H)-pyridinone (CAS 89284-22-0)
- 4-Methyloxazole-5-carbonyl chloride (CAS 62348-24-7)
- Methyl (E)-3-chloro-2-cyanoacrylate (CAS 73619-75-7)
- Ethyl 9-oxo-9,10-dihydroacridine-4-carboxylate (CAS 59749-05-2)
- N-(1,2,3,4-TEtrahydroacridin-9-yl)butane-1,4-diamine dihydrochloride (CAS 2108381-92-4)
- 7-Bromo-2-iodobenzo[d]thiazole (CAS 1175278-13-3)
- (2-(4-(Difluoromethoxy)-3-isopropoxyphenyl)oxazol-4-yl)methanamine (CAS 1574286-10-4)
- (S)-4,4-Difluoropyrrolidine-2-carboxylic acid hydrobromide (CAS 72180-29-1)
- 4-Chloro-5-((4-fluorobenzyl)oxy)-2-propylpyridazin-3(2H)-one (CAS 88094-08-0)
- 3-(Ethylamino)-5-methylisoxazole-4-carboxylic acid (CAS 946197-87-1)
- H-Gly-Gly-His-OH (CAS 7451-76-5)
- 4-((2-Ethyl-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)methyl)benzoic acid (CAS 1401728-86-6)
- CBP501 Affinity Peptide trifluoroacetate salt (CAS 1351804-17-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com