2-Bromo-1-(3,5-dichloro-2-hydroxyphenyl)ethan-1-one CAS 53244-91-0
| CAS No. | 53244-91-0 |
| Molecular Formula | C8H5BrCl2O2 |
| Molecular Weight | 283.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Bromo-1-(3,5-dichloro-2-hydroxyphenyl)ethan-1-one (CAS 53244-91-0), molecular formula C8H5BrCl2O2 and molecular weight 283.93 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Bromo-1-(3,5-dichloro-2-hydroxyphenyl)ethan-1-one (C8H5BrCl2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Bromo-1-(3,5-dichloro-2-hydroxyphenyl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5BrCl2O2 |
| Molecular Weight | 283.93 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl/Br-containing |
Related Bromo Standards
- (4-Bromo-2-chlorophenoxy)acetyl chloride (CAS 110630-87-0)
- Methyl 3-bromo-4,5-dichlorobenzoate (CAS 1160574-77-5)
- Methyl 4-bromo-3,5-dichlorobenzoate (CAS 117738-81-5)
- Methyl 6-bromo-2,3-dichlorobenzoate (CAS 1257856-85-1)
- Methyl 5-bromo-2,4-dichlorobenzoate (CAS 1305712-91-7)
- 2-Bromo-1-(3,4-dichloro-2-hydroxyphenyl)ethan-1-one (CAS 1344688-06-7)
- Methyl 4-bromo-2,5-dichlorobenzoate (CAS 1542664-63-0)
- 1-(4-Bromo-3-chloro-2-hydroxyphenyl)-2-chloroethanone (CAS 1706436-37-4)
Recommended Standards
- Methyl 3-bromo-2,4-dichlorobenzoate (CAS 1820705-16-5)
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- 2-Bromo-2-(3,4-dichlorophenyl)acetic acid (CAS 72191-59-4)
- 2-Bromo-4,6-dichlorobenzoic acid methyl ester (CAS 943975-32-4)
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