2-Chloro-n-hexylacetamide CAS 5326-81-8
| CAS No. | 5326-81-8 |
| Molecular Formula | C8H16ClNO |
| Molecular Weight | 177.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-n-hexylacetamide.
2-Chloro-n-hexylacetamide (CAS 5326-81-8) is a high-purity analytical reference standard with the molecular formula C8H16ClNO and a molecular weight of 177.67 g/mol.
The molecular framework of 2-Chloro-n-hexylacetamide (C8H16ClNO) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Chloro-n-hexylacetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H16ClNO |
| Molecular Weight | 177.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-chloro-N-(pentan-2-yl)propanamide (CAS 1016808-29-9)
- 2-chloro-N-(3-methylbutyl)propanamide (CAS 1016813-78-7)
- 2-Chloro-n-(pentan-3-yl)propanamide (CAS 1016888-28-0)
- 2-Chloro-n-(2,2-dimethylpropyl)-n-methylacetamide (CAS 1247465-01-5)
- 2-Chloro-n-(3,3-dimethylbutyl)acetamide (CAS 1259915-95-1)
- (R)-1-chloro-3-(piperidin-1-yl)propan-2-ol (CAS 1416332-55-2)
- 2-chloro-N-(2-methylbutan-2-yl)propanamide (CAS 42276-10-8)
- 2-Chloro-n,n-bis(propan-2-yl)acetamide (CAS 7403-66-9)
Recommended Standards
- 2-Chloro-N,N-dipropylacetamide (CAS 2315-37-9)
- 2-Chloro-n-pentylpropanamide (CAS 87603-55-2)
- 4-Chloro-n-(2-methylpropyl)butanamide (CAS 544416-14-0)
- 4-Chloro-n,n-diethylbutanamide (CAS 56794-28-6)
- n-Cyclohexyl-2-fluoroaniline (CAS 1019482-89-3)
- 6-Iodo-1,4-dimethylquinolin-2(1H)-one (CAS 1420793-28-7)
- 1-(2-Cyclohexylethyl)thiourea (CAS 1183120-27-5)
- 2-(benzylamino)-1-(3-methylphenyl)ethan-1-ol (CAS 94673-34-4)
- 1-(Thiophen-2-yl)-N-((1-(2,2,2-trifluoroethyl)-1H-pyrazol-5-yl)methyl)methanamine hydrochloride (CAS 1856067-99-6)
- 2-(4-((Ethoxycarbonyl)amino)phenyl)acetic acid (CAS 91134-09-7)
- Methyl 3-(N,N-dimethylsulfamoyl)benzoate (CAS 823833-29-0)
- 4-(4-Chlorophenyl)-2-(isopropylthio)-6-(p-tolyl)nicotinonitrile (CAS 444154-03-4)
- tert-Butyl 4-(tert-butyl)thiazole-2-carboxylate (CAS 79247-76-0)
- Peptide YY (3-36) (canine, mouse, porcine, rat) trifluoroacetate salt (CAS 126339-09-1)
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