4-Chloro-2-(hydroxymethyl)phenol CAS 5330-38-1
| CAS No. | 5330-38-1 |
| Molecular Formula | C7H7ClO2 |
| Molecular Weight | 158.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-2-(hydroxymethyl)phenol.
4-Chloro-2-(hydroxymethyl)phenol (CAS 5330-38-1) is a high-purity analytical reference standard with the molecular formula C7H7ClO2 and a molecular weight of 158.58 g/mol.
The molecular framework of 4-Chloro-2-(hydroxymethyl)phenol (C7H7ClO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-2-(hydroxymethyl)phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7ClO2 |
| Molecular Weight | 158.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 2-Chloro-4-(hydroxymethyl)phenol (CAS 105960-29-0)
- 2-Chloro-1-(furan-2-yl)propan-1-one (CAS 106430-52-8)
- 3-Chloro-2-(hydroxymethyl)phenol (CAS 1094627-55-0)
- 4-Chloro-3-hydroxybenzyl alcohol (CAS 1261598-26-8)
- 2-Chloro-1-(4-methylfuran-2-yl)ethanone (CAS 133674-52-9)
- 2-Chloro-1-(3-methylfuran-2-yl)ethan-1-one (CAS 1502390-71-7)
- 2-Chloro-1-(2-methylfuran-3-yl)ethan-1-one (CAS 1543126-21-1)
- 3-Chloro-4-(hydroxymethyl)phenol (CAS 171569-42-9)
Recommended Standards
- 3-Chloro-5-methylbenzene-1,2-diol (CAS 3978-66-3)
- 4-Chloro-3-(hydroxymethyl)phenol (CAS 876299-47-7)
- 3-Chloro-5-methoxyphenol (CAS 65262-96-6)
- 4-CHLORO-5-METHYLBENZENE-1,3-DIOL (CAS 3446-05-7)
- 3-(1-Methyl-1h-imidazol-5-yl)isoxazole-5-carboxylic acid (CAS 1369236-60-1)
- 4,6-Dichloro-5-nitro-2-[4-(1-piperidinylmethyl)phenyl]pyrimidine (CAS 1353506-55-4)
- 1-(4-Methoxybenzyl)-5-phenyl-1H-imidazole (CAS 1192811-38-3)
- 3-Ethylazetidin-3-amine dihydrochloride (CAS 1427397-56-5)
- 2-(1-Ethyl-1H-pyrazol-5-yl)piperidine (CAS 1339854-76-0)
- 1-tert-Butyl 3-ethyl trans-4-(trifluoromethyl)pyrrolidine-1,3-dicarboxylate (CAS 1428776-53-7)
- 5-Bromo-2-(3-fluorophenyl)pyridazin-3(2h)-one (CAS 2090941-95-8)
- N-Ethyl Fluprostenol Carboxamide (CAS 1005193-64-5)
- (E)-3-(4-Fluorophenyl)-2-Propen-1-ol (CAS 124980-95-6)
- Insulin aspart (CAS 116094-23-6)
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