3-Chloro-4-phenoxyaniline CAS 5335-29-5
| CAS No. | 5335-29-5 |
| Molecular Formula | C12H10ClNO |
| Molecular Weight | 219.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Chloro-4-phenoxyaniline is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Chloro-4-phenoxyaniline (CAS 5335-29-5) is a high-purity analytical reference standard with the molecular formula C12H10ClNO and a molecular weight of 219.67 g/mol.
The molecular framework of 3-Chloro-4-phenoxyaniline (C12H10ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Chloro-4-phenoxyaniline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10ClNO |
| Molecular Weight | 219.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 2-(4-Bromophenoxy)butanoyl chloride (CAS 17520-86-4)
- 6-Methylpyrimidine-4-carbohydrazide (CAS 89691-95-2)
- 4-Bromo-3-(methylthio)phenol (CAS 1379306-40-7)
- 1-Azidoheptane (CAS 44961-22-0)
- 2-(Piperidin-4-yl)-6-(pyrrolidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridine (CAS 1422060-93-2)
- Neuropeptide Y (13-36) (human, rat) (CAS 122341-40-6)
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