Ethyl 1-butyl-4,5-dioxopyrrolidine-3-carboxylate CAS 5336-46-9
| CAS No. | 5336-46-9 |
| Molecular Formula | C12H14N2O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl 1-butyl-4,5-dioxopyrrolidine-3-carboxylate (CAS 5336-46-9), molecular formula C12H14N2OHCl and molecular weight 238.72 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 1-butyl-4,5-dioxopyrrolidine-3-carboxylate (C12H14N2OHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14N2O HCl |
| Molecular Weight | 238.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
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- 1-(5-Bromo-2-(trifluoromethyl)pyridin-4-yl)-2,2,2-trifluoroethanol (CAS 1375303-18-6)
- 2-Chloro-N-(3-(4-methoxyphenyl)-4-oxo-4H-chromen-2-yl)acetamide (CAS 1017420-44-8)
- 2-Iodo-5-methoxypyridine (CAS 163129-79-1)
- Des-Val23-Tirzepatide (CAS CATO-CPTD788950)
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